Tissue expression of PIGV - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PIGV
Gene description	Phosphatidylinositol glycan anchor biosynthesis, class V
Protein class	Disease related genes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PIGV (HGNC Symbol)
Synonyms	FLJ20477
Description	Phosphatidylinositol glycan anchor biosynthesis, class V (HGNC Symbol)
Entrez gene summary	This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Chromosome	1
Cytoband	p36.11
Chromosome location (bp)	26787472 - 26798398
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000060642 (version 83.38)
Entrez gene	55650
UniProt	Q9NUD9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NUD9
Antibodypedia	PIGV antibodies

PROTEIN BROWSER

PIGV-001	PIGV-002	PIGV-003	PIGV-005	PIGV-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PIGV-001 ENSP00000078527 ENST00000078527	Q9NUD9 [Direct mapping] GPI mannosyltransferase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Disease related genes Show all	GO:0000030 [mannosyltransferase activity] GO:0004584 [dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006501 [C-terminal protein lipidation] GO:0006506 [GPI anchor biosynthetic process] GO:0016021 [integral component of membrane] GO:0016254 [preassembly of GPI anchor in ER membrane] GO:0031501 [mannosyltransferase complex] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0097502 [mannosylation] Show all	493 aa 55.7 kDa	No	8
PIGV-002 ENSP00000363260 ENST00000374145	Q9NUD9 [Direct mapping] GPI mannosyltransferase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Disease related genes Show all	GO:0000030 [mannosyltransferase activity] GO:0004584 [dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006501 [C-terminal protein lipidation] GO:0006506 [GPI anchor biosynthetic process] GO:0016021 [integral component of membrane] GO:0016254 [preassembly of GPI anchor in ER membrane] GO:0031501 [mannosyltransferase complex] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0097502 [mannosylation] Show all	493 aa 55.7 kDa	No	8
PIGV-003 ENSP00000399067 ENST00000430292	A0A0A0MSQ1 [Direct mapping] GPI mannosyltransferase 2 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0004584 [dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity] GO:0006506 [GPI anchor biosynthetic process] GO:0097502 [mannosylation] Show all	72 aa 8.1 kDa	No	0
PIGV-005 ENSP00000388425 ENST00000431541	X1WI27 [Direct mapping] GPI mannosyltransferase 2 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0004584 [dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity] GO:0006506 [GPI anchor biosynthetic process] GO:0097502 [mannosylation] Show all	121 aa 13.5 kDa	No	0
PIGV-006 ENSP00000406080 ENST00000455364	A0A0A0MSX6 [Direct mapping] GPI mannosyltransferase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0004584 [dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity] GO:0006506 [GPI anchor biosynthetic process] GO:0016021 [integral component of membrane] GO:0097502 [mannosylation] Show all	182 aa 20.1 kDa	No	3