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Gene name

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AHRR
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

AHRR

Gene description

Aryl-hydrocarbon receptor repressor

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enhanced (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

AHRR (HGNC Symbol)

Synonyms

AHH, AHHR, bHLHe77, KIAA1234

Description

Aryl-hydrocarbon receptor repressor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]

Chromosome

5

Cytoband

p15.33

Chromosome location (bp)

304176 - 438291

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000063438 (version 83.38)

Entrez gene

57491

UniProt

A9YTQ3 (UniProt - Evidence at protein level)

neXtProt

NX_A9YTQ3

Antibodypedia

AHRR antibodies

PROTEIN BROWSER

AHRR-001
AHRR-002
AHRR-003
AHRR-004
AHRR-006
AHRR-007
AHRR-008
AHRR-009
AHRR-011

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AHRR-001
ENSP00000323816
ENST00000316418
A9YTQ3 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0003677 [DNA binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009410 [response to xenobiotic stimulus]
GO:0046983 [protein dimerization activity]
Show all
719 aa
78.3 kDa
No 0
AHRR-002
ENSP00000424601
ENST00000505113
A9YTQ3 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0003677 [DNA binding]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009410 [response to xenobiotic stimulus]
GO:0046983 [protein dimerization activity]
Show all
701 aa
76.3 kDa
No 0
AHRR-003
ENSP00000424880
ENST00000512529
D6RF73 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0009410 [response to xenobiotic stimulus]
Show all
547 aa
59.4 kDa
No 0
AHRR-004
ENSP00000426932
ENST00000506456
D6RE68 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0009410 [response to xenobiotic stimulus]
Show all
557 aa
60.5 kDa
No 0
AHRR-006
ENSP00000430914
ENST00000514523
E5RHE0 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0009410 [response to xenobiotic stimulus]
Show all
12 aa
1.5 kDa
No 0
AHRR-007
ENSP00000428893
ENST00000510400
E5RFG4 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0009410 [response to xenobiotic stimulus]
GO:0046983 [protein dimerization activity]
Show all
157 aa
17.3 kDa
No 0
AHRR-008
ENSP00000429944
ENST00000504625
E5RGQ2 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0009410 [response to xenobiotic stimulus]
GO:0046983 [protein dimerization activity]
Show all
81 aa
9.3 kDa
No 0
AHRR-009
ENSP00000430842
ENST00000515206
G3V143 [Direct mapping]
Aryl hydrocarbon receptor repressor; HCG1985585, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0009410 [response to xenobiotic stimulus]
GO:0046983 [protein dimerization activity]
Show all
139 aa
15.7 kDa
No 0
AHRR-011
ENSP00000426076
ENST00000511487
H0YA43 [Direct mapping]
Aryl hydrocarbon receptor repressor
Show all
Predicted intracellular proteins
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding]
GO:0009410 [response to xenobiotic stimulus]
Show all
215 aa
23.3 kDa
No 0

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The Human Protein Atlas project is funded
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