Tissue expression of AHRR - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	AHRR
Gene description	Aryl-hydrocarbon receptor repressor
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enhanced (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	AHRR (HGNC Symbol)
Synonyms	AHH, AHHR, bHLHe77, KIAA1234
Description	Aryl-hydrocarbon receptor repressor (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
Chromosome	5
Cytoband	p15.33
Chromosome location (bp)	304176 - 438291
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000063438 (version 83.38)
Entrez gene	57491
UniProt	A9YTQ3 (UniProt - Evidence at protein level)
neXtProt	NX_A9YTQ3
Antibodypedia	AHRR antibodies

PROTEIN BROWSER

AHRR-001	AHRR-002	AHRR-003	AHRR-004	AHRR-006	AHRR-007	AHRR-008	AHRR-009	AHRR-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AHRR-001 ENSP00000323816 ENST00000316418	A9YTQ3 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0003677 [DNA binding] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0009410 [response to xenobiotic stimulus] GO:0046983 [protein dimerization activity] Show all	719 aa 78.3 kDa	No	0
AHRR-002 ENSP00000424601 ENST00000505113	A9YTQ3 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0003677 [DNA binding] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0009410 [response to xenobiotic stimulus] GO:0046983 [protein dimerization activity] Show all	701 aa 76.3 kDa	No	0
AHRR-003 ENSP00000424880 ENST00000512529	D6RF73 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0009410 [response to xenobiotic stimulus] Show all	547 aa 59.4 kDa	No	0
AHRR-004 ENSP00000426932 ENST00000506456	D6RE68 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0009410 [response to xenobiotic stimulus] Show all	557 aa 60.5 kDa	No	0
AHRR-006 ENSP00000430914 ENST00000514523	E5RHE0 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0009410 [response to xenobiotic stimulus] Show all	12 aa 1.5 kDa	No	0
AHRR-007 ENSP00000428893 ENST00000510400	E5RFG4 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0009410 [response to xenobiotic stimulus] GO:0046983 [protein dimerization activity] Show all	157 aa 17.3 kDa	No	0
AHRR-008 ENSP00000429944 ENST00000504625	E5RGQ2 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0009410 [response to xenobiotic stimulus] GO:0046983 [protein dimerization activity] Show all	81 aa 9.3 kDa	No	0
AHRR-009 ENSP00000430842 ENST00000515206	G3V143 [Direct mapping] Aryl hydrocarbon receptor repressor; HCG1985585, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0009410 [response to xenobiotic stimulus] GO:0046983 [protein dimerization activity] Show all	139 aa 15.7 kDa	No	0
AHRR-011 ENSP00000426076 ENST00000511487	H0YA43 [Direct mapping] Aryl hydrocarbon receptor repressor Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001191 [transcriptional repressor activity, RNA polymerase II transcription factor binding] GO:0009410 [response to xenobiotic stimulus] Show all	215 aa 23.3 kDa	No	0