Cell atlas - ADCK1 - The Human Protein Atlas

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ADCK1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ADCK1
Gene description	AarF domain containing kinase 1
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Mouse	Localized to the Nucleoplasm in mouse cells.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA055014
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA055014	A-431	Nucleoplasm
	HPA055014	MCF7	Nucleoplasm
	HPA055014	U-2 OS	Nucleoplasm

MOUSE CELLS

Main location

Nucleoplasm

Mouse gene

ENSMUSG00000021044 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA055014	NIH 3T3	Nucleoplasm

GENE INFORMATION
Gene name	ADCK1 (HGNC Symbol)
Synonyms	FLJ39600
Description	AarF domain containing kinase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	77800083 - 77935012
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000063761 (version 83.38)
Entrez gene	57143
UniProt	Q86TW2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86TW2
Antibodypedia	ADCK1 antibodies

PROTEIN BROWSER

ADCK1-001	ADCK1-002	ADCK1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADCK1-001 ENSP00000238561 ENST00000238561	Q86TW2 [Direct mapping] Uncharacterized aarF domain-containing protein kinase 1 Show all	Enzymes Kinases Atypical kinases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0005576 [extracellular region] GO:0005739 [mitochondrion] GO:0006468 [protein phosphorylation] Show all	523 aa 59.7 kDa	Yes	0
ADCK1-002 ENSP00000339663 ENST00000341211	Q86TW2 [Direct mapping] Uncharacterized aarF domain-containing protein kinase 1 Show all	Enzymes Kinases Atypical kinases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0005576 [extracellular region] GO:0006468 [protein phosphorylation] Show all	455 aa 52 kDa	Yes	0
ADCK1-007 ENSP00000451549 ENST00000557501	G3V426 [Direct mapping] Uncharacterized aarF domain-containing protein kinase 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		266 aa 30.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.