Cell atlas - CDON - The Human Protein Atlas

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CDON

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CDON
Gene description	Cell adhesion associated, oncogene regulated
Protein class	Disease related genes Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (RH-30, AF22)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RH-30, AF22) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CDON (HGNC Symbol)
Synonyms	CDO, CDON1, ORCAM
Description	Cell adhesion associated, oncogene regulated (HGNC Symbol)
Entrez gene summary	This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011]
Chromosome	11
Cytoband	q24.2
Chromosome location (bp)	125955796 - 126063335
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000064309 (version 83.38)
Entrez gene	50937
UniProt	Q4KMG0 (UniProt - Evidence at protein level)
neXtProt	NX_Q4KMG0
Antibodypedia	CDON antibodies

PROTEIN BROWSER

CDON-001	CDON-002	CDON-004	CDON-005	CDON-007	CDON-008	CDON-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDON-001 ENSP00000376458 ENST00000392693	Q4KMG0 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001708 [cell fate specification] GO:0001934 [positive regulation of protein phosphorylation] GO:0002088 [lens development in camera-type eye] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0007520 [myoblast fusion] GO:0009952 [anterior/posterior pattern specification] GO:0009986 [cell surface] GO:0010172 [embryonic body morphogenesis] GO:0014816 [skeletal muscle satellite cell differentiation] GO:0016021 [integral component of membrane] GO:0021987 [cerebral cortex development] GO:0031012 [extracellular matrix] GO:0042692 [muscle cell differentiation] GO:0043410 [positive regulation of MAPK cascade] GO:0043497 [regulation of protein heterodimerization activity] GO:0045664 [regulation of neuron differentiation] GO:0045666 [positive regulation of neuron differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048598 [embryonic morphogenesis] GO:0048643 [positive regulation of skeletal muscle tissue development] GO:0051057 [positive regulation of small GTPase mediated signal transduction] GO:0051146 [striated muscle cell differentiation] GO:0051149 [positive regulation of muscle cell differentiation] GO:0060059 [embryonic retina morphogenesis in camera-type eye] GO:2000179 [positive regulation of neural precursor cell proliferation] Show all	1287 aa 139.1 kDa	Yes	1
CDON-002 ENSP00000263577 ENST00000263577	Q4KMG0 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] GO:0031012 [extracellular matrix] GO:0042692 [muscle cell differentiation] GO:0051149 [positive regulation of muscle cell differentiation] Show all	1264 aa 136.5 kDa	Yes	1
CDON-004 ENSP00000436755 ENST00000534661	H0YEX4 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	650 aa 69.6 kDa	No	0
CDON-005 ENSP00000434212 ENST00000531586	E9PRD8 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	165 aa 17.6 kDa	Yes	0
CDON-007 ENSP00000432901 ENST00000531738	E9PN78 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	641 aa 69.8 kDa	No	1
CDON-008 ENSP00000437176 ENST00000534818	E9PNF2 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	111 aa 11.7 kDa	Yes	0
CDON-010 ENSP00000436940 ENST00000527967	E9PPQ7 [Direct mapping] Cell adhesion molecule-related/down-regulated by oncogenes Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	143 aa 15 kDa	Yes	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.