Expression of TMEM161A in cancer - Summary - The Human Protein Atlas

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TMEM161A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM161A
Gene description	Transmembrane protein 161A
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membranous expression in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA043365
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PROGNOSTIC SUMMARY
Prognostic marker in stomach cancer (favourable).
Stomach cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043365

GENE INFORMATION
Gene name	TMEM161A (HGNC Symbol)
Synonyms	FLJ20422, FLJ39645
Description	Transmembrane protein 161A (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	19119169 - 19138513
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000064545 (version 83.38)
Entrez gene	54929
UniProt	Q9NX61 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NX61
Antibodypedia	TMEM161A antibodies

PROTEIN BROWSER

TMEM161A-002	TMEM161A-004	TMEM161A-006	TMEM161A-007	TMEM161A-009	TMEM161A-011	TMEM161A-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM161A-002 ENSP00000404208 ENST00000450333	Q9NX61 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0032526 [response to retinoic acid] GO:0034599 [cellular response to oxidative stress] GO:0034644 [cellular response to UV] GO:0045739 [positive regulation of DNA repair] GO:1902230 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage] Show all	376 aa 41.6 kDa	Yes	5
TMEM161A-004 ENSP00000162044 ENST00000162044	Q9NX61 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0032526 [response to retinoic acid] GO:0034599 [cellular response to oxidative stress] GO:0034644 [cellular response to UV] GO:0045739 [positive regulation of DNA repair] GO:1902230 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage] Show all	479 aa 53.6 kDa	Yes	8
TMEM161A-006 ENSP00000467300 ENST00000587583	K7EPA3 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	454 aa 50.6 kDa	Yes	7
TMEM161A-007 ENSP00000467793 ENST00000587915	K7EQE7 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	145 aa 16.9 kDa	No	2
TMEM161A-009 ENSP00000467649 ENST00000587096	K7EQ34 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	315 aa 35.9 kDa	No	6
TMEM161A-011 ENSP00000476977 ENST00000592369	V9GYP8 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	61 aa 6.9 kDa	No	2
TMEM161A-012 ENSP00000465840 ENST00000587925	K7EKY7 [Direct mapping] Transmembrane protein 161A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	194 aa 21.8 kDa	No	4

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The Human Protein Atlas

The Human Protein Atlas project is funded
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