Expression of SNX24 in cancer - Summary - The Human Protein Atlas

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SNX24

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SNX24
Gene description	Sorting nexin 24
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA044566
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable), renal cancer (favourable) and liver cancer (unfavourable).
Endometrial cancer p<0.001 Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044566

GENE INFORMATION
Gene name	SNX24 (HGNC Symbol)
Synonyms	SBBI31
Description	Sorting nexin 24 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q23.2
Chromosome location (bp)	122843439 - 123029354
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000064652 (version 83.38)
Entrez gene	28966
UniProt	Q9Y343 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y343
Antibodypedia	SNX24 antibodies

PROTEIN BROWSER

SNX24-001	SNX24-002	SNX24-003	SNX24-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SNX24-001 ENSP00000261369 ENST00000261369	Q9Y343 [Direct mapping] Sorting nexin-24 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0010314 [phosphatidylinositol-5-phosphate binding] GO:0015031 [protein transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0032266 [phosphatidylinositol-3-phosphate binding] GO:0035091 [phosphatidylinositol binding] GO:0070273 [phosphatidylinositol-4-phosphate binding] Show all	169 aa 19.8 kDa	No	0
SNX24-002 ENSP00000378837 ENST00000395451	A8MXB7 [Direct mapping] Sorting nexin-24 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0035091 [phosphatidylinositol binding] Show all	202 aa 23.7 kDa	No	0
SNX24-003 ENSP00000424149 ENST00000513881	Q9Y343 [Direct mapping] Sorting nexin-24 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0015031 [protein transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0035091 [phosphatidylinositol binding] Show all	159 aa 18.6 kDa	No	0
SNX24-004 ENSP00000422535 ENST00000506996	Q9Y343 [Direct mapping] Sorting nexin-24 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0015031 [protein transport] GO:0030659 [cytoplasmic vesicle membrane] GO:0035091 [phosphatidylinositol binding] Show all	159 aa 18.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.