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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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FAM107B
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

FAM107B

Gene description

Family with sequence similarity 107, member B

Protein class

Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

20
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression with additional extracellular and plasma positivity in several different tissue types.

ANTIBODY IHC RELIABILITY

Data reliability
description

Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

Uncertain based on 1 antibody.
HPA039661
SHOW MORE

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA039661

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most liver cancers along with several testicular and urothelial cancers showed moderate cytoplasmic positivity. Tumour cells in general were weakly stained or negative.

GENE INFORMATION

Gene name

FAM107B (HGNC Symbol)

Synonyms

C10orf45, FLJ45505, MGC11034

Description

Family with sequence similarity 107, member B (HGNC Symbol)

Entrez gene summary

Chromosome

10

Cytoband

p13

Chromosome location (bp)

14518557 - 14774897

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065809 (version 83.38)

Entrez gene

83641

UniProt

Q9H098 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H098

Antibodypedia

FAM107B antibodies

PROTEIN BROWSER

«
FAM107B-001
FAM107B-002
FAM107B-003
FAM107B-004
FAM107B-005
FAM107B-008
FAM107B-009
FAM107B-010
FAM107B-011
FAM107B-012
FAM107B-013
FAM107B-014
FAM107B-015
FAM107B-016
FAM107B-017
FAM107B-018
FAM107B-019
FAM107B-020
FAM107B-021
FAM107B-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM107B-001
ENSP00000181796
ENST00000181796
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007605 [sensory perception of sound]
Show all
306 aa
34.8 kDa
Yes 0
FAM107B-002
ENSP00000367731
ENST00000378470
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-003
ENSP00000367728
ENST00000378467
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-004
ENSP00000418120
ENST00000468747
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-005
ENSP00000367719
ENST00000378458
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-008
ENSP00000367723
ENST00000378462
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-009
ENSP00000418330
ENST00000496330
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-010
ENSP00000413676
ENST00000452706
C9JW51 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
128 aa
15.2 kDa
No 0
FAM107B-011
ENSP00000367726
ENST00000378465
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-012
ENSP00000420314
ENST00000488576
C9JP05 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
93 aa
11.2 kDa
No 0
FAM107B-013
ENSP00000397949
ENST00000442012
X6RET8 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
90 aa
10.8 kDa
No 0
FAM107B-014
ENSP00000417782
ENST00000478076
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-015
ENSP00000420444
ENST00000468492
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-016
ENSP00000419603
ENST00000479731
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0
FAM107B-017
ENSP00000417242
ENST00000475786
C9J3Q3 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
101 aa
12.2 kDa
No 0
FAM107B-018
ENSP00000417845
ENST00000482277
C9J6Y8 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
84 aa
10 kDa
No 0
FAM107B-019
ENSP00000418395
ENST00000494865
C9J6N5 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
125 aa
14.9 kDa
No 0
FAM107B-020
ENSP00000419064
ENST00000472095
C9JYP1 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
67 aa
8 kDa
No 0
FAM107B-021
ENSP00000420249
ENST00000489100
C9JQ40 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
126 aa
15 kDa
No 0
FAM107B-201
ENSP00000479842
ENST00000622567
Q9H098 [Direct mapping]
Protein FAM107B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
131 aa
15.6 kDa
No 0

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