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DIP2B

GENERAL INFORMATION

Gene name

 DIP2B

Gene description

 Disco-interacting protein 2 homolog B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA046133 , HPA056045
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
N/A
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 DIP2B (HGNC Symbol)

Synonyms

 FLJ34278, KIAA1463

Description

 Disco-interacting protein 2 homolog B (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]

Chromosome

 12

Cytoband

 q13.12

Chromosome location (bp)

 50504985 - 50748667

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000066084 (version 83.38)

Entrez gene

 57609

UniProt

 Q9P265 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9P265

Antibodypedia

 DIP2B antibodies

PROTEIN BROWSER
DIP2B-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DIP2B-002
ENSP00000301180
ENST00000301180
Q9P265 [Direct mapping]
Disco-interacting protein 2 homolog B
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003824 [catalytic activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0008134 [transcription factor binding]
GO:0008150 [biological_process]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0070062 [extracellular exosome]
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 1576 aa
171.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.