Expression of MPPED2 in cancer - Summary - The Human Protein Atlas

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MPPED2

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	MPPED2
Gene description	Metallophosphoesterase domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HaCaT, RT4, SH-SY5Y)
HPA (normal tissue):	Tissue enhanced (cervix, uterine, thyroid gland)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	MPPED2 (HGNC Symbol)
Synonyms	239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638
Description	Metallophosphoesterase domain containing 2 (HGNC Symbol)
Entrez gene summary	This gene likely encodes a metallophosphoesterase. The encoded protein may play a role a brain development. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Chromosome	11
Cytoband	p14.1
Chromosome location (bp)	30384493 - 30586872
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000066382 (version 83.38)
Entrez gene	744
UniProt	Q15777 (UniProt - Evidence at protein level)
neXtProt	NX_Q15777
Antibodypedia	MPPED2 antibodies

PROTEIN BROWSER

MPPED2-001	MPPED2-002	MPPED2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MPPED2-001 ENSP00000388258 ENST00000448418	Q15777 [Direct mapping] Metallophosphoesterase MPPED2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007399 [nervous system development] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0046872 [metal ion binding] Show all	277 aa 31.5 kDa	No	0
MPPED2-002 ENSP00000431805 ENST00000528686	F2Z346 [Direct mapping] Metallophosphoesterase MPPED2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 9.2 kDa	No	0
MPPED2-005 ENSP00000350833 ENST00000358117	Q15777 [Direct mapping] Metallophosphoesterase MPPED2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007399 [nervous system development] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0046872 [metal ion binding] Show all	294 aa 33.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.