Expression of ISOC1 in cancer - Summary - The Human Protein Atlas

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ISOC1

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	ISOC1
Gene description	Isochorismatase domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	ISOC1 (HGNC Symbol)
Synonyms	CGI-111
Description	Isochorismatase domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q23.3
Chromosome location (bp)	129094751 - 129114028
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000066583 (version 83.38)
Entrez gene	51015
UniProt	Q96CN7 (UniProt - Evidence at protein level)
neXtProt	NX_Q96CN7
Antibodypedia	ISOC1 antibodies

PROTEIN BROWSER

ISOC1-001	ISOC1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ISOC1-001 ENSP00000173527 ENST00000173527	Q96CN7 [Direct mapping] Isochorismatase domain-containing protein 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005777 [peroxisome] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0070062 [extracellular exosome] Show all	298 aa 32.2 kDa	No	0
ISOC1-002 ENSP00000421273 ENST00000514194	D6RGE2 [Direct mapping] Isochorismatase domain-containing protein 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	188 aa 20.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.