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MEF2A

GENERAL INFORMATION

Gene name

 MEF2A

Gene description

 Myocyte enhancer factor 2A

Protein class

 Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 9
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
CAB004499
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and stomach cancer (unfavourable).
Renal cancer p<0.001
Stomach cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Glioma

STAINING SUMMARY
CAB004499

GENE INFORMATION

Gene name

 MEF2A (HGNC Symbol)

Synonyms

 RSRFC4, RSRFC9

Description

 Myocyte enhancer factor 2A (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

Chromosome

 15

Cytoband

 q26.3

Chromosome location (bp)

 99565417 - 99716466

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000068305 (version 83.38)

Entrez gene

 4205

UniProt

 Q02078 (UniProt - Evidence at protein level)

neXtProt

 NX_Q02078

Antibodypedia

 MEF2A antibodies

PROTEIN BROWSER
MEF2A-001
MEF2A-002
MEF2A-003
MEF2A-004
MEF2A-005
MEF2A-008
MEF2A-009
MEF2A-010
MEF2A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MEF2A-001
ENSP00000346389
ENST00000354410
Q02078 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Cancer-related genes
   Mutational cancer driver genes
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002 [mitochondrial genome maintenance]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000790 [nuclear chromatin]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0019901 [protein kinase binding]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035035 [histone acetyltransferase binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045087 [innate immune response]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048311 [mitochondrion distribution]
GO:0048813 [dendrite morphogenesis]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0055005 [ventricular cardiac myofibril assembly]
GO:0061337 [cardiac conduction]
GO:0070375 [ERK5 cascade]
GO:0071277 [cellular response to calcium ion]
Show all
 499 aa
53.9 kDa 		No 0
MEF2A-002
ENSP00000453441
ENST00000557785
Q02078 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Cancer-related genes
   Mutational cancer driver genes
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002 [mitochondrial genome maintenance]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000790 [nuclear chromatin]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035035 [histone acetyltransferase binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048311 [mitochondrion distribution]
GO:0048813 [dendrite morphogenesis]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0055005 [ventricular cardiac myofibril assembly]
GO:0061337 [cardiac conduction]
GO:0070375 [ERK5 cascade]
GO:0071277 [cellular response to calcium ion]
Show all
 497 aa
53.5 kDa 		No 0
MEF2A-003
ENSP00000454120
ENST00000558812
Q02078 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Cancer-related genes
   Mutational cancer driver genes
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002 [mitochondrial genome maintenance]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000790 [nuclear chromatin]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035035 [histone acetyltransferase binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048311 [mitochondrion distribution]
GO:0048813 [dendrite morphogenesis]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0055005 [ventricular cardiac myofibril assembly]
GO:0061337 [cardiac conduction]
GO:0070375 [ERK5 cascade]
GO:0071277 [cellular response to calcium ion]
Show all
 437 aa
46.5 kDa 		No 0
MEF2A-004
ENSP00000399460
ENST00000449277
Q02078 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Cancer-related genes
   Mutational cancer driver genes
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002 [mitochondrial genome maintenance]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000790 [nuclear chromatin]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035035 [histone acetyltransferase binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048311 [mitochondrion distribution]
GO:0048813 [dendrite morphogenesis]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0055005 [ventricular cardiac myofibril assembly]
GO:0061337 [cardiac conduction]
GO:0070375 [ERK5 cascade]
GO:0071277 [cellular response to calcium ion]
Show all
 429 aa
45.6 kDa 		No 0
MEF2A-005
ENSP00000453095
ENST00000557942
Q02078 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Cancer-related genes
   Mutational cancer driver genes
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002 [mitochondrial genome maintenance]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000790 [nuclear chromatin]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035035 [histone acetyltransferase binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048311 [mitochondrion distribution]
GO:0048813 [dendrite morphogenesis]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0055005 [ventricular cardiac myofibril assembly]
GO:0061337 [cardiac conduction]
GO:0070375 [ERK5 cascade]
GO:0071277 [cellular response to calcium ion]
Show all
 505 aa
54.4 kDa 		No 0
MEF2A-008
ENSP00000453478
ENST00000560493
H0YM62 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
 85 aa
10.1 kDa 		No 0
MEF2A-009
ENSP00000452989
ENST00000559903
H0YKY6 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
 77 aa
9.2 kDa 		No 0
MEF2A-010
ENSP00000454023
ENST00000558049
H0YNI2 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
 38 aa
4.6 kDa 		No 0
MEF2A-201
ENSP00000337202
ENST00000338042
Q02078 [Direct mapping]
Myocyte-specific enhancer factor 2A
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Cancer-related genes
   Mutational cancer driver genes
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000002 [mitochondrial genome maintenance]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000790 [nuclear chromatin]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001105 [RNA polymerase II transcription coactivator activity]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035035 [histone acetyltransferase binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045087 [innate immune response]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046332 [SMAD binding]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048311 [mitochondrion distribution]
GO:0048813 [dendrite morphogenesis]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0055005 [ventricular cardiac myofibril assembly]
GO:0061337 [cardiac conduction]
GO:0070375 [ERK5 cascade]
GO:0071277 [cellular response to calcium ion]
Show all
 497 aa
53.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.