Expression of PRR11 in cancer - Summary - The Human Protein Atlas

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PRR11

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRR11
Gene description	Proline rich 11
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA023923
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), liver cancer (unfavourable), lung cancer (unfavourable), endometrial cancer (unfavourable) and pancreatic cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Lung cancer p<0.001 Endometrial cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023923

GENE INFORMATION
Gene name	PRR11 (HGNC Symbol)
Synonyms	FLJ11029
Description	Proline rich 11 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q22
Chromosome location (bp)	59155499 - 59204705
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000068489 (version 83.38)
Entrez gene	55771
UniProt	Q96HE9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96HE9
Antibodypedia	PRR11 antibodies

PROTEIN BROWSER

PRR11-001	PRR11-004	PRR11-005	PRR11-006	PRR11-007	PRR11-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRR11-001 ENSP00000262293 ENST00000262293	Q96HE9 [Direct mapping] Proline-rich protein 11 D2SNZ4 [Target identity:100%; Query identity:100%] Proline rich 11, isoform CRA_a; Transcription repressor of MHCII Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0051726 [regulation of cell cycle] Show all	360 aa 40.1 kDa	No	0
PRR11-004 ENSP00000464392 ENST00000577457	J3QRV0 [Direct mapping] Proline-rich protein 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		22 aa 2.8 kDa	No	0
PRR11-005 ENSP00000464048 ENST00000578777	J3QR53 [Direct mapping] Proline-rich protein 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		199 aa 22.4 kDa	No	0
PRR11-006 ENSP00000463292 ENST00000582995	J3QKY4 [Direct mapping] Proline-rich protein 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		144 aa 16.9 kDa	No	0
PRR11-007 ENSP00000463871 ENST00000582004	J3QQS2 [Direct mapping] Proline-rich protein 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		53 aa 5.9 kDa	No	0
PRR11-201 ENSP00000481852 ENST00000614081	Q96HE9 [Direct mapping] Proline-rich protein 11 D2SNZ4 [Target identity:100%; Query identity:100%] Proline rich 11, isoform CRA_a; Transcription repressor of MHCII Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0051726 [regulation of cell cycle] Show all	360 aa 40.1 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.