Expression of FUNDC1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

FUNDC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FUNDC1
Gene description	FUN14 domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA038773
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable) and testis cancer (favourable).
Urothelial cancer p<0.001 Testis cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038773

GENE INFORMATION
Gene name	FUNDC1 (HGNC Symbol)
Synonyms	MGC51029
Description	FUN14 domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011]
Chromosome	X
Cytoband	p11.3
Chromosome location (bp)	44523639 - 44543001
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000069509 (version 83.38)
Entrez gene	139341
UniProt	Q8IVP5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IVP5
Antibodypedia	FUNDC1 antibodies

PROTEIN BROWSER

FUNDC1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FUNDC1-001 ENSP00000367284 ENST00000378045	Q8IVP5 [Direct mapping] FUN14 domain-containing protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000422 [mitophagy] GO:0001666 [response to hypoxia] GO:0005515 [protein binding] GO:0005741 [mitochondrial outer membrane] GO:0031307 [integral component of mitochondrial outer membrane] Show all	155 aa 17.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.