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Most cancer tissues displayed moderate to strong cytoplasmic immunoreactivity with a granular pattern. Lymphomas, melanomas and testicular cancers were weakly stained.
Most cancer tissues displayed moderate to strong granular cytoplasmic staining. Several cases of lymphomas, prostate and urothelial cancer were negative.
GENE INFORMATION
Gene name
MAOB
Synonyms
Description
Monoamine oxidase B (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]