Expression of TMEM260 in cancer - Summary - The Human Protein Atlas

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TMEM260

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM260
Gene description	Transmembrane protein 260
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Tissue enhanced (cervix, uterine)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA003502
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PROGNOSTIC SUMMARY
Prognostic marker in lung cancer (favourable).
Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA003502

GENE INFORMATION
Gene name	TMEM260 (HGNC Symbol)
Synonyms	C14orf101, FLJ20392
Description	Transmembrane protein 260 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q22.3
Chromosome location (bp)	56488354 - 56650606
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000070269 (version 83.38)
Entrez gene	54916
UniProt	Q9NX78 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NX78
Antibodypedia	TMEM260 antibodies

PROTEIN BROWSER

TMEM260-001	TMEM260-008	TMEM260-015	TMEM260-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM260-001 ENSP00000261556 ENST00000261556	Q9NX78 [Direct mapping] Transmembrane protein 260 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	707 aa 79.5 kDa	No	8
TMEM260-008 ENSP00000451677 ENST00000556810	G3V4A2 [Direct mapping] Transmembrane protein 260 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	74 aa 7.9 kDa	No	1
TMEM260-015 ENSP00000451695 ENST00000555046	H0YJK2 [Direct mapping] Transmembrane protein 260 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		41 aa 4.6 kDa	No	0
TMEM260-201 ENSP00000441934 ENST00000538838	Q0VAA1 [Direct mapping] C14orf101 protein; Transmembrane protein 260 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	409 aa 44.5 kDa	No	9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.