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Most malignancies showed moderate to strong nuclear positivity.
GENE INFORMATION
Gene name
JMJD6 (HGNC Symbol)
Synonyms
KIAA0585, PTDSR, PTDSR1
Description
Jumonji domain containing 6 (HGNC Symbol)
Entrez gene summary
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]