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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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CFAP20
  • TISSUE

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    CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

CFAP20

Gene description

Cilia and flagella associated protein 20

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Uncertain based on 1 antibody.
HPA018195
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA018195

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

A majority of skin, breast, gastric, colorectal and pancreatic cancers as well as several cervical, lung and liver cancers showed moderate to strong cytoplasmic staining. Remaining malignancies were weakly stained or negative.

GENE INFORMATION

Gene name

CFAP20 (HGNC Symbol)

Synonyms

C16orf80, fSAP23, GTL3

Description

Cilia and flagella associated protein 20 (HGNC Symbol)

Entrez gene summary

Chromosome

16

Cytoband

q21

Chromosome location (bp)

58113588 - 58129450

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070761 (version 83.38)

Entrez gene

29105

UniProt

Q9Y6A4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6A4

Antibodypedia

CFAP20 antibodies

PROTEIN BROWSER

CFAP20-001
CFAP20-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CFAP20-001
ENSP00000262498
ENST00000262498
Q9Y6A4 [Direct mapping]
Cilia- and flagella-associated protein 20
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005814 [centriole]
GO:0005874 [microtubule]
GO:0005929 [cilium]
GO:0007275 [multicellular organismal development]
GO:0018095 [protein polyglutamylation]
GO:0036064 [ciliary basal body]
GO:0044822 [poly(A) RNA binding]
GO:0060271 [cilium morphogenesis]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
GO:0070062 [extracellular exosome]
GO:2000147 [positive regulation of cell motility]
GO:2000253 [positive regulation of feeding behavior]
Show all
193 aa
22.8 kDa
No 0
CFAP20-007
ENSP00000455220
ENST00000565880
H3BPA3 [Direct mapping]
Cilia- and flagella-associated protein 20
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
109 aa
12.4 kDa
No 0

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