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Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATION
Gene name
STK10 (HGNC Symbol)
Synonyms
LOK, PRO2729
Description
Serine/threonine kinase 10 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]
Enzymes ENZYME proteins Transferases Kinases STE Ser/Thr protein kinases Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0007049 [cell cycle] GO:0007346 [regulation of mitotic cell cycle] GO:0023014 [signal transduction by protein phosphorylation] GO:0031098 [stress-activated protein kinase signaling cascade] GO:0032147 [activation of protein kinase activity] GO:0042801 [polo kinase kinase activity] GO:0042802 [identical protein binding] GO:0042803 [protein homodimerization activity] GO:0042981 [regulation of apoptotic process] GO:0046777 [protein autophosphorylation] GO:0070062 [extracellular exosome] GO:0071593 [lymphocyte aggregation] GO:2000401 [regulation of lymphocyte migration]
