Expression of SIDT1 in cancer - Summary - The Human Protein Atlas

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SIDT1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SIDT1
Gene description	SID1 transmembrane family, member 1
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (MCF7, PC-3, RT4, T-47d)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA035862
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable) and cervical cancer (favourable).
Urothelial cancer p<0.001 Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA035862

GENE INFORMATION
Gene name	SIDT1 (HGNC Symbol)
Synonyms	FLJ20174, SID-1
Description	SID1 transmembrane family, member 1 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q13.2
Chromosome location (bp)	113532296 - 113629578
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000072858 (version 83.38)
Entrez gene	54847
UniProt	Q9NXL6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NXL6
Antibodypedia	SIDT1 antibodies

PROTEIN BROWSER

SIDT1-001	SIDT1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SIDT1-001 ENSP00000264852 ENST00000264852	Q9NXL6 [Direct mapping] SID1 transmembrane family member 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0033227 [dsRNA transport] GO:0051033 [RNA transmembrane transporter activity] Show all	827 aa 93.8 kDa	Yes	>9
SIDT1-201 ENSP00000377416 ENST00000393830	Q9NXL6 [Direct mapping] SID1 transmembrane family member 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0033227 [dsRNA transport] GO:0051033 [RNA transmembrane transporter activity] Show all	832 aa 94.4 kDa	Yes	>9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.