Expression of NCBP3 in cancer - Summary - The Human Protein Atlas

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NCBP3

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NCBP3
Gene description	Nuclear cap binding subunit 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA008959 , HPA013195
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PROGNOSTIC SUMMARY
Prognostic marker in melanoma (unfavourable) and prostate cancer (unfavourable).
Melanoma p<0.001 Prostate cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA008959	HPA013195

GENE INFORMATION
Gene name	NCBP3 (HGNC Symbol)
Synonyms	C17orf85, ELG, HSA277841
Description	Nuclear cap binding subunit 3 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.2
Chromosome location (bp)	3802165 - 3846251
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000074356 (version 83.38)
Entrez gene	55421
UniProt	Q53F19 (UniProt - Evidence at protein level)
neXtProt	NX_Q53F19
Antibodypedia	NCBP3 antibodies

PROTEIN BROWSER

NCBP3-001	NCBP3-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NCBP3-001 ENSP00000373657 ENST00000389005	Q53F19 [Direct mapping] Uncharacterized protein C17orf85 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0044822 [poly(A) RNA binding] Show all	620 aa 70.6 kDa	No	0
NCBP3-006 ENSP00000466165 ENST00000576523	K7ELP6 [Direct mapping] Uncharacterized protein C17orf85 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		80 aa 9.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.