Expression of ANKRD13A in cancer - Summary - The Human Protein Atlas

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ANKRD13A

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANKRD13A
Gene description	Ankyrin repeat domain 13A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in immune cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA039488 , HPA043218
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable) and ovarian cancer (unfavourable).
Head and neck cancer p<0.001 Ovarian cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039488	HPA043218

GENE INFORMATION
Gene name	ANKRD13A (HGNC Symbol)
Synonyms	ANKRD13, NY-REN-25
Description	Ankyrin repeat domain 13A (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.11
Chromosome location (bp)	109999186 - 110039763
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000076513 (version 83.38)
Entrez gene	88455
UniProt	Q8IZ07 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IZ07
Antibodypedia	ANKRD13A antibodies

PROTEIN BROWSER

ANKRD13A-001	ANKRD13A-006	ANKRD13A-008	ANKRD13A-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD13A-001 ENSP00000261739 ENST00000261739	Q8IZ07 [Direct mapping] Ankyrin repeat domain-containing protein 13A Q3ZTS7 [Target identity:100%; Query identity:100%] Ankyrin repeat domain 13, isoform CRA_b; NY-REN-25 antigen Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005770 [late endosome] GO:0005886 [plasma membrane] Show all	590 aa 67.6 kDa	No	0
ANKRD13A-006 ENSP00000449781 ENST00000547639	H0YIN8 [Direct mapping] Ankyrin repeat domain-containing protein 13A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		302 aa 34.7 kDa	No	0
ANKRD13A-008 ENSP00000474745 ENST00000547419	S4R3U2 [Direct mapping] Ankyrin repeat domain-containing protein 13A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		173 aa 19.9 kDa	No	0
ANKRD13A-010 ENSP00000447110 ENST00000551491	F8W150 [Direct mapping] Ankyrin repeat domain-containing protein 13A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		83 aa 9.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.