Tissue expression of UBE2T - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	UBE2T
Gene description	Ubiquitin-conjugating enzyme E2T
Protein class	Disease related genes Enzymes Potential drug targets Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Tissue enhanced (testis)
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	UBE2T (HGNC Symbol)
Synonyms	FANCT, HSPC150
Description	Ubiquitin-conjugating enzyme E2T (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene catalyzes the covalent attachment of ubiquitin to protein substrates. Defects in this gene have been associated with Fanconi anemia of complementation group T. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Chromosome	1
Cytoband	q32.1
Chromosome location (bp)	202331657 - 202341980
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000077152 (version 83.38)
Entrez gene	29089
UniProt	Q9NPD8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NPD8
Antibodypedia	UBE2T antibodies

PROTEIN BROWSER

UBE2T-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UBE2T-001 ENSP00000356243 ENST00000367274	Q9NPD8 [Direct mapping] Ubiquitin-conjugating enzyme E2 T A0A024R9A9 [Target identity:100%; Query identity:100%] Ubiquitin-conjugating enzyme E2T (Putative), isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003682 [chromatin binding] GO:0004842 [ubiquitin-protein transferase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006281 [DNA repair] GO:0006513 [protein monoubiquitination] GO:0006974 [cellular response to DNA damage stimulus] GO:0031625 [ubiquitin protein ligase binding] GO:0035519 [protein K29-linked ubiquitination] GO:0036297 [interstrand cross-link repair] GO:0044314 [protein K27-linked ubiquitination] GO:0051865 [protein autoubiquitination] GO:0061630 [ubiquitin protein ligase activity] GO:0061631 [ubiquitin conjugating enzyme activity] GO:0070534 [protein K63-linked ubiquitination] GO:0070936 [protein K48-linked ubiquitination] GO:0070979 [protein K11-linked ubiquitination] GO:0085020 [protein K6-linked ubiquitination] Show all	197 aa 22.5 kDa	No	0