Cell atlas - BRINP1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

BRINP1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Microtubules

Human cell
	Microtubules

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	BRINP1
Gene description	Bone morphogenetic protein/retinoic acid inducible neural-specific 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the microtubules.
RNA cell category	Group enriched (NTERA-2, SCLC-21H, SH-SY5Y)
Protein evidence	Evidence at protein level
Main location	Localized to the Microtubules (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA038828
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NTERA-2, SCLC-21H, SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the microtubules.

Main location

Microtubules (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA038828	A-431	Microtubules
	HPA038828	U-2 OS	Microtubules
	HPA038828	U-251 MG	Microtubules

GENE INFORMATION
Gene name	BRINP1 (HGNC Symbol)
Synonyms	DBC1, DBCCR1, FAM5A
Description	Bone morphogenetic protein/retinoic acid inducible neural-specific 1 (HGNC Symbol)
Entrez gene summary	This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq, Jul 2008]
Chromosome	9
Cytoband	q33.1
Chromosome location (bp)	119153458 - 119369467
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000078725 (version 83.38)
Entrez gene	1620
UniProt	O60477 (UniProt - Evidence at protein level)
neXtProt	NX_O60477
Antibodypedia	BRINP1 antibodies

PROTEIN BROWSER

BRINP1-001	BRINP1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BRINP1-001 ENSP00000265922 ENST00000265922	O60477 [Direct mapping] BMP/retinoic acid-inducible neural-specific protein 1 Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007050 [cell cycle arrest] GO:0008219 [cell death] GO:0045666 [positive regulation of neuron differentiation] GO:0045786 [negative regulation of cell cycle] GO:0045930 [negative regulation of mitotic cell cycle] GO:0071300 [cellular response to retinoic acid] Show all	761 aa 88.8 kDa	Yes	0
BRINP1-002 ENSP00000363075 ENST00000373964	O60477 [Direct mapping] BMP/retinoic acid-inducible neural-specific protein 1 Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007050 [cell cycle arrest] GO:0008219 [cell death] GO:0045786 [negative regulation of cell cycle] Show all	320 aa 37.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.