Tissue expression of OSBPL6 - Summary - The Human Protein Atlas

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OSBPL6

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	OSBPL6
Gene description	Oxysterol binding protein-like 6
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex)
GTEx:	Tissue enhanced (skeletal muscle)
FANTOM5:	Tissue enhanced (pituitary gland, skeletal muscle)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in skeletal muscle.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Antibody staining in cells/structures not annotated, view images.
Reliability score	Supported based on 1 antibody. HPA032131
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

Skeletal muscle

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skeletal muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pituitary gland, skeletal muscle)

GENE INFORMATION
Gene name	OSBPL6 (HGNC Symbol)
Synonyms	ORP6
Description	Oxysterol binding protein-like 6 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q31.2
Chromosome location (bp)	178194481 - 178402891
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000079156 (version 83.38)
Entrez gene	114880
UniProt	Q9BZF3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BZF3
Antibodypedia	OSBPL6 antibodies

PROTEIN BROWSER

OSBPL6-001	OSBPL6-002	OSBPL6-003	OSBPL6-004	OSBPL6-005	OSBPL6-006	OSBPL6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OSBPL6-001 ENSP00000190611 ENST00000190611	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	934 aa 106.3 kDa	No	0
OSBPL6-002 ENSP00000376293 ENST00000392505	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	959 aa 109 kDa	No	0
OSBPL6-003 ENSP00000349591 ENST00000357080	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	508 aa 57 kDa	No	0
OSBPL6-004 ENSP00000387248 ENST00000409045	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	903 aa 102.6 kDa	No	0
OSBPL6-005 ENSP00000386885 ENST00000409631	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	898 aa 102.3 kDa	No	0
OSBPL6-006 ENSP00000318723 ENST00000315022	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	938 aa 106.9 kDa	No	0
OSBPL6-201 ENSP00000352713 ENST00000359685	Q9BZF3 [Direct mapping] Oxysterol-binding protein-related protein 6 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006869 [lipid transport] GO:0008289 [lipid binding] GO:0031965 [nuclear membrane] GO:0097038 [perinuclear endoplasmic reticulum] Show all	898 aa 102.3 kDa	No	0

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The Project

The Human Protein Atlas

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