Cell atlas - COL5A3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

COL5A3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	COL5A3
Gene description	Collagen, type V, alpha 3
Protein class	Cancer-related genes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (ASC TERT1, WM-115, BJ hTERT+, BJ, BJ hTERT+ SV40 Large T+)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (ASC TERT1, WM-115, BJ hTERT+, BJ, BJ hTERT+ SV40 Large T+) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	COL5A3
Synonyms
Description	Collagen, type V, alpha 3 (HGNC Symbol)
Entrez gene summary	This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	9959561 - 10010471
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000080573 (version 83.38)
Entrez gene	50509
UniProt	P25940 (UniProt - Evidence at protein level)
neXtProt	NX_P25940
Antibodypedia	COL5A3 antibodies

PROTEIN BROWSER

COL5A3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COL5A3-001 ENSP00000264828 ENST00000264828	P25940 [Direct mapping] Collagen alpha-3(V) chain Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005201 [extracellular matrix structural constituent] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005581 [collagen trimer] GO:0005588 [collagen type V trimer] GO:0005788 [endoplasmic reticulum lumen] GO:0007160 [cell-matrix adhesion] GO:0007411 [axon guidance] GO:0008201 [heparin binding] GO:0022617 [extracellular matrix disassembly] GO:0030198 [extracellular matrix organization] GO:0030199 [collagen fibril organization] GO:0030574 [collagen catabolic process] GO:0031012 [extracellular matrix] GO:0043394 [proteoglycan binding] GO:0043588 [skin development] GO:0070062 [extracellular exosome] Show all	1745 aa 172.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.