Expression of COBLL1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

COBLL1

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	COBLL1
Gene description	Cordon-bleu WH2 repeat protein-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	12
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membranous expression in most cell types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Paired antibodies with high similarity supports the protein expression profile.
Reliability score	Supported based on 2 antibodies. HPA044933 , HPA053344
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044933	HPA053344

GENE INFORMATION
Gene name	COBLL1 (HGNC Symbol)
Synonyms	KIAA0977
Description	Cordon-bleu WH2 repeat protein-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q24.3
Chromosome location (bp)	164653624 - 164843679
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000082438 (version 83.38)
Entrez gene	22837
UniProt	Q53SF7 (UniProt - Evidence at protein level)
neXtProt	NX_Q53SF7
Antibodypedia	COBLL1 antibodies

PROTEIN BROWSER

COBLL1-001	COBLL1-003	COBLL1-004	COBLL1-007	COBLL1-008	COBLL1-011	COBLL1-016	COBLL1-018	COBLL1-019	COBLL1-020	COBLL1-025	COBLL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COBLL1-001 ENSP00000387326 ENST00000409184	Q53SF7 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0003785 [actin monomer binding] GO:0030041 [actin filament polymerization] GO:0051639 [actin filament network formation] GO:0070062 [extracellular exosome] Show all	1168 aa 127.8 kDa	No	0
COBLL1-003 ENSP00000364607 ENST00000375458	Q53SF7 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0003785 [actin monomer binding] GO:0030041 [actin filament polymerization] GO:0051639 [actin filament network formation] GO:0070062 [extracellular exosome] Show all	1128 aa 123.9 kDa	No	0
COBLL1-004 ENSP00000341360 ENST00000342193	Q53SF7 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0003785 [actin monomer binding] GO:0030041 [actin filament polymerization] GO:0051639 [actin filament network formation] GO:0070062 [extracellular exosome] Show all	1166 aa 127.9 kDa	No	0
COBLL1-007 ENSP00000397520 ENST00000456693	C9J8C4 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		226 aa 25.1 kDa	No	0
COBLL1-008 ENSP00000409237 ENST00000444537	C9JK90 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		170 aa 19 kDa	No	0
COBLL1-011 ENSP00000400146 ENST00000452626	H7C1G2 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		258 aa 29.2 kDa	No	0
COBLL1-016 ENSP00000406062 ENST00000448708	C9JAU3 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		157 aa 17.6 kDa	No	0
COBLL1-018 ENSP00000397835 ENST00000439313	C9J5Y6 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		163 aa 18.2 kDa	No	0
COBLL1-019 ENSP00000388110 ENST00000445474	F8WEK0 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		148 aa 16 kDa	No	0
COBLL1-020 ENSP00000387967 ENST00000414843	C9JWZ0 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		139 aa 15.5 kDa	No	0
COBLL1-025 ENSP00000487041 ENST00000629362	A0A0D9SG04 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] Show all	1233 aa 134.9 kDa	No	0
COBLL1-201 ENSP00000376478 ENST00000392717	Q53SF7 [Direct mapping] Cordon-bleu protein-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003779 [actin binding] GO:0003785 [actin monomer binding] GO:0030041 [actin filament polymerization] GO:0051639 [actin filament network formation] GO:0070062 [extracellular exosome] Show all	1204 aa 131.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.