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KIF3C

GENERAL INFORMATION

Gene name

 KIF3C

Gene description

 Kinesin family member 3C

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (SH-SY5Y)
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable), melanoma (favourable) and renal cancer (unfavourable).
Endometrial cancer p<0.001
Melanoma p<0.001
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 KIF3C

Synonyms

Description

 Kinesin family member 3C (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p23.3

Chromosome location (bp)

 25926596 - 25982749

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000084731 (version 83.38)

Entrez gene

 3797

UniProt

 O14782 (UniProt - Evidence at protein level)

neXtProt

 NX_O14782

Antibodypedia

 KIF3C antibodies

PROTEIN BROWSER
KIF3C-001
KIF3C-002
KIF3C-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIF3C-001
ENSP00000264712
ENST00000264712
O14782 [Direct mapping]
Kinesin-like protein KIF3C
A2RU78 [Target identity:100%; Query identity:100%]
Kinesin-like protein
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003774 [motor activity]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006996 [organelle organization]
GO:0007018 [microtubule-based movement]
GO:0007596 [blood coagulation]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0030705 [cytoskeleton-dependent intracellular transport]
GO:0072372 [primary cilium]
GO:0072384 [organelle transport along microtubule]
GO:0097542 [ciliary tip]
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 793 aa
89.5 kDa 		No 0
KIF3C-002
ENSP00000385030
ENST00000405914
O14782 [Direct mapping]
Kinesin-like protein KIF3C
A2RU78 [Target identity:100%; Query identity:100%]
Kinesin-like protein
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006996 [organelle organization]
GO:0007018 [microtubule-based movement]
GO:0007596 [blood coagulation]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II]
GO:0030705 [cytoskeleton-dependent intracellular transport]
GO:0072372 [primary cilium]
GO:0097542 [ciliary tip]
Show all
 793 aa
89.5 kDa 		No 0
KIF3C-201
ENSP00000480682
ENST00000614152
A0A087WX26 [Direct mapping]
Kinesin-like protein
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030705 [cytoskeleton-dependent intracellular transport]
Show all
 792 aa
89.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.