Expression of WDR47 in cancer - Summary - The Human Protein Atlas

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WDR47

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	WDR47
Gene description	WD repeat domain 47
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression at variable levels in most cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending retesting.
Reliability score	Approved based on 2 antibodies. HPA027287 , HPA027289
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable).
Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027287	HPA027289

GENE INFORMATION
Gene name	WDR47 (HGNC Symbol)
Synonyms	KIAA0893
Description	WD repeat domain 47 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	108970214 - 109042113
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000085433 (version 83.38)
Entrez gene	22911
UniProt	O94967 (UniProt - Evidence at protein level)
neXtProt	NX_O94967
Antibodypedia	WDR47 antibodies

PROTEIN BROWSER

WDR47-001	WDR47-002	WDR47-003	WDR47-004	WDR47-005	WDR47-006	WDR47-007	WDR47-008	WDR47-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
WDR47-001 ENSP00000358982 ENST00000369965	O94967 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007275 [multicellular organismal development] Show all	920 aa 102 kDa	No	0
WDR47-002 ENSP00000358979 ENST00000369962	O94967 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007275 [multicellular organismal development] Show all	919 aa 101.9 kDa	No	0
WDR47-003 ENSP00000354339 ENST00000361054	O94967 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007275 [multicellular organismal development] Show all	891 aa 98.5 kDa	No	0
WDR47-004 ENSP00000383599 ENST00000400794	O94967 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007275 [multicellular organismal development] Show all	927 aa 102.9 kDa	No	0
WDR47-005 ENSP00000434289 ENST00000530772	E9PR96 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	173 aa 20.1 kDa	No	0
WDR47-006 ENSP00000437171 ENST00000529074	E9PNF6 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		93 aa 11 kDa	No	0
WDR47-007 ENSP00000434868 ENST00000531337	E9PN15 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		57 aa 6.7 kDa	No	0
WDR47-008 ENSP00000433452 ENST00000528747	E9PKZ6 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	106 aa 12.4 kDa	No	0
WDR47-201 ENSP00000350301 ENST00000357672	A0A0A0MRE6 [Direct mapping] WD repeat-containing protein 47 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	893 aa 98.7 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.