Cell atlas - AQP6 - The Human Protein Atlas

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AQP6

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	AQP6
Gene description	Aquaporin 6, kidney specific
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	AQP6 (HGNC Symbol)
Synonyms	AQP2L
Description	Aquaporin 6, kidney specific (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q13.12
Chromosome location (bp)	49967194 - 49977139
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000086159 (version 83.38)
Entrez gene	363
UniProt	Q13520 (UniProt - Evidence at transcript level)
neXtProt	NX_Q13520
Antibodypedia	AQP6 antibodies

PROTEIN BROWSER

AQP6-001	AQP6-004	AQP6-201	AQP6-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AQP6-001 ENSP00000320247 ENST00000315520	Q13520 [Direct mapping] Aquaporin-6 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005253 [anion channel activity] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0006833 [water transport] GO:0007588 [excretion] GO:0009992 [cellular water homeostasis] GO:0015250 [water channel activity] GO:0015254 [glycerol channel activity] GO:0015793 [glycerol transport] GO:0016020 [membrane] GO:0016324 [apical plasma membrane] GO:0030658 [transport vesicle membrane] GO:0042476 [odontogenesis] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	282 aa 29.4 kDa	No	6
AQP6-004 ENSP00000449830 ENST00000551733	F8VW87 [Direct mapping] Aquaporin-6 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015254 [glycerol channel activity] GO:0015793 [glycerol transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] Show all	108 aa 11.2 kDa	No	1
AQP6-201 ENSP00000477688 ENST00000615425	Q13520 [Direct mapping] Aquaporin-6 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005253 [anion channel activity] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0006833 [water transport] GO:0007588 [excretion] GO:0009992 [cellular water homeostasis] GO:0015112 [nitrate transmembrane transporter activity] GO:0015250 [water channel activity] GO:0015254 [glycerol channel activity] GO:0015706 [nitrate transport] GO:0015793 [glycerol transport] GO:0016020 [membrane] GO:0016324 [apical plasma membrane] GO:0030658 [transport vesicle membrane] GO:0042476 [odontogenesis] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	282 aa 29.4 kDa	No	6
AQP6-202 ENSP00000477759 ENST00000618286	Q9NSV5 [Direct mapping] Aquaporin-6; Putative uncharacterized protein DKFZp434D2030 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015254 [glycerol channel activity] GO:0015793 [glycerol transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] Show all	163 aa 17.1 kDa	No	3

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.