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PSMC5

GENERAL INFORMATION

Gene name

 PSMC5

Gene description

 Proteasome 26S subunit, ATPase 5

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA017871
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PSMC5 (HGNC Symbol)

Synonyms

 p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1

Description

 Proteasome 26S subunit, ATPase 5 (HGNC Symbol)

Entrez gene summary

 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Chromosome

 17

Cytoband

 q23.3

Chromosome location (bp)

 63827152 - 63832026

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000087191 (version 83.38)

Entrez gene

 5705

UniProt

 P62195 (UniProt - Evidence at protein level)

neXtProt

 NX_P62195

Antibodypedia

 PSMC5 antibodies

PROTEIN BROWSER
PSMC5-001
PSMC5-004
PSMC5-006
PSMC5-008
PSMC5-011
PSMC5-018
PSMC5-019
PSMC5-020
PSMC5-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PSMC5-001
ENSP00000310572
ENST00000310144
P62195 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000502 [proteasome complex]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0003712 [transcription cofactor activity]
GO:0005102 [receptor binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005838 [proteasome regulatory particle]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006521 [regulation of cellular amino acid metabolic process]
GO:0006595 [polyamine metabolic process]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0008134 [transcription factor binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0012501 [programmed cell death]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016234 [inclusion body]
GO:0016787 [hydrolase activity]
GO:0016887 [ATPase activity]
GO:0017025 [TBP-class protein binding]
GO:0022624 [proteasome accessory complex]
GO:0030163 [protein catabolic process]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031410 [cytoplasmic vesicle]
GO:0031531 [thyrotropin-releasing hormone receptor binding]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0036402 [proteasome-activating ATPase activity]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042981 [regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050852 [T cell receptor signaling pathway]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0070062 [extracellular exosome]
GO:0072562 [blood microparticle]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090261 [positive regulation of inclusion body assembly]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 406 aa
45.6 kDa 		No 0
PSMC5-004
ENSP00000462495
ENST00000580864
P62195 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000502 [proteasome complex]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006521 [regulation of cellular amino acid metabolic process]
GO:0006595 [polyamine metabolic process]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0008134 [transcription factor binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0012501 [programmed cell death]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016787 [hydrolase activity]
GO:0016887 [ATPase activity]
GO:0017025 [TBP-class protein binding]
GO:0022624 [proteasome accessory complex]
GO:0030163 [protein catabolic process]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031410 [cytoplasmic vesicle]
GO:0031531 [thyrotropin-releasing hormone receptor binding]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0036402 [proteasome-activating ATPase activity]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042981 [regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050852 [T cell receptor signaling pathway]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0070062 [extracellular exosome]
GO:0072562 [blood microparticle]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 398 aa
44.8 kDa 		No 0
PSMC5-006
ENSP00000463938
ENST00000581882
P62195 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000502 [proteasome complex]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006521 [regulation of cellular amino acid metabolic process]
GO:0006595 [polyamine metabolic process]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0008134 [transcription factor binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0012501 [programmed cell death]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016787 [hydrolase activity]
GO:0016887 [ATPase activity]
GO:0017025 [TBP-class protein binding]
GO:0022624 [proteasome accessory complex]
GO:0030163 [protein catabolic process]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031410 [cytoplasmic vesicle]
GO:0031531 [thyrotropin-releasing hormone receptor binding]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0036402 [proteasome-activating ATPase activity]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042981 [regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050852 [T cell receptor signaling pathway]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0070062 [extracellular exosome]
GO:0072562 [blood microparticle]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 398 aa
44.8 kDa 		No 0
PSMC5-008
ENSP00000464405
ENST00000579708
J3QRW1 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0017025 [TBP-class protein binding]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0036402 [proteasome-activating ATPase activity]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 143 aa
15.8 kDa 		No 0
PSMC5-011
ENSP00000463801
ENST00000582130
J3QQM1 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0017025 [TBP-class protein binding]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0036402 [proteasome-activating ATPase activity]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 263 aa
29.3 kDa 		No 0
PSMC5-018
ENSP00000463549
ENST00000581842
J3QLH6 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0017025 [TBP-class protein binding]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0036402 [proteasome-activating ATPase activity]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 215 aa
24.2 kDa 		No 0
PSMC5-019
ENSP00000464602
ENST00000585123
J3QSA9 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0017025 [TBP-class protein binding]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0036402 [proteasome-activating ATPase activity]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 257 aa
28.7 kDa 		No 0
PSMC5-020
ENSP00000462098
ENST00000584320
J3KRP2 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0017025 [TBP-class protein binding]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0036402 [proteasome-activating ATPase activity]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 241 aa
27.2 kDa 		No 0
PSMC5-201
ENSP00000364970
ENST00000375812
P62195 [Direct mapping]
26S protease regulatory subunit 8
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0000209 [protein polyubiquitination]
GO:0000278 [mitotic cell cycle]
GO:0000502 [proteasome complex]
GO:0002223 [stimulatory C-type lectin receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006521 [regulation of cellular amino acid metabolic process]
GO:0006595 [polyamine metabolic process]
GO:0006915 [apoptotic process]
GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007411 [axon guidance]
GO:0008134 [transcription factor binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0008540 [proteasome regulatory particle, base subcomplex]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010467 [gene expression]
GO:0012501 [programmed cell death]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016787 [hydrolase activity]
GO:0016887 [ATPase activity]
GO:0017025 [TBP-class protein binding]
GO:0022624 [proteasome accessory complex]
GO:0030163 [protein catabolic process]
GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process]
GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process]
GO:0031410 [cytoplasmic vesicle]
GO:0031531 [thyrotropin-releasing hormone receptor binding]
GO:0031595 [nuclear proteasome complex]
GO:0031597 [cytosolic proteasome complex]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0036402 [proteasome-activating ATPase activity]
GO:0038061 [NIK/NF-kappaB signaling]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042981 [regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043488 [regulation of mRNA stability]
GO:0044281 [small molecule metabolic process]
GO:0045087 [innate immune response]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045899 [positive regulation of RNA polymerase II transcriptional preinitiation complex assembly]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0050852 [T cell receptor signaling pathway]
GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition]
GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle]
GO:0070062 [extracellular exosome]
GO:0072562 [blood microparticle]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
GO:1901800 [positive regulation of proteasomal protein catabolic process]
Show all
 398 aa
44.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.