Expression of C20orf194 in cancer - Summary - The Human Protein Atlas

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C20orf194

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C20orf194
Gene description	Chromosome 20 open reading frame 194
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in the CNS, peripheral nerves and in muscle tissue.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Antibody staining in cells/structures not annotated, view images.
Reliability score	Approved based on 2 antibodies. HPA052103 , HPA067418
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable) and renal cancer (favourable).
Pancreatic cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052103	HPA067418

GENE INFORMATION
Gene name	C20orf194 (HGNC Symbol)
Synonyms	DKFZp434N061
Description	Chromosome 20 open reading frame 194 (HGNC Symbol)
Entrez gene summary	This gene encodes an uncharacterized protein with a C-terminal coiled-coil region. The gene is located on chromosome 20p13 in a 1.8 Mb region linked to a spinocerebellar ataxia phenotype, but this gene does not appear to be a disease candidate. [provided by RefSeq, Dec 2011]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	3249305 - 3407625
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000088854 (version 83.38)
Entrez gene	25943
UniProt	Q5TEA3 (UniProt - Evidence at protein level)
neXtProt	NX_Q5TEA3
Antibodypedia	C20orf194 antibodies

PROTEIN BROWSER

C20orf194-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C20orf194-001 ENSP00000252032 ENST00000252032	Q5TEA3 [Direct mapping] Uncharacterized protein C20orf194 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		1177 aa 132.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.