Expression of CDIP1 in cancer - Summary - The Human Protein Atlas

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CDIP1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CDIP1
Gene description	Cell death-inducing p53 target 1
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	12
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (RPMI-8226)
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic and nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA049352
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and pancreatic cancer (favourable).
Renal cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049352

GENE INFORMATION
Gene name	CDIP1 (HGNC Symbol)
Synonyms	C16orf5, CDIP, LITAFL
Description	Cell death-inducing p53 target 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	4510675 - 4538828
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000089486 (version 83.38)
Entrez gene	29965
UniProt	Q9H305 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H305
Antibodypedia	CDIP1 antibodies

PROTEIN BROWSER

CDIP1-001	CDIP1-002	CDIP1-004	CDIP1-005	CDIP1-006	CDIP1-007	CDIP1-011	CDIP1-012	CDIP1-013	CDIP1-014	CDIP1-015	CDIP1-017

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDIP1-001 ENSP00000457877 ENST00000567695	Q9H305 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006915 [apoptotic process] GO:0033209 [tumor necrosis factor-mediated signaling pathway] GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] Show all	208 aa 21.9 kDa	No	1
CDIP1-002 ENSP00000455462 ENST00000563507	Q9H305 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006915 [apoptotic process] GO:0033209 [tumor necrosis factor-mediated signaling pathway] GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] Show all	169 aa 17.9 kDa	No	1
CDIP1-004 ENSP00000454994 ENST00000563332	Q9H305 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006915 [apoptotic process] GO:0033209 [tumor necrosis factor-mediated signaling pathway] GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] Show all	208 aa 21.9 kDa	No	1
CDIP1-005 ENSP00000382508 ENST00000399599	Q9H305 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006915 [apoptotic process] GO:0033209 [tumor necrosis factor-mediated signaling pathway] GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] Show all	208 aa 21.9 kDa	No	1
CDIP1-006 ENSP00000456461 ENST00000564828	H3BRY7 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted intracellular proteins Show all		52 aa 5.5 kDa	No	0
CDIP1-007 ENSP00000455050 ENST00000562334	Q9H305 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006915 [apoptotic process] GO:0033209 [tumor necrosis factor-mediated signaling pathway] GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] Show all	129 aa 13.8 kDa	No	1
CDIP1-011 ENSP00000457370 ENST00000563186	H3BTX4 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted intracellular proteins Show all		111 aa 11.4 kDa	No	0
CDIP1-012 ENSP00000457255 ENST00000562579	H3BTN7 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted intracellular proteins Show all		133 aa 13.4 kDa	No	0
CDIP1-013 ENSP00000465412 ENST00000588381	K7EK15 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted intracellular proteins Show all		95 aa 9.7 kDa	No	0
CDIP1-014 ENSP00000468627 ENST00000586728	K7ESA8 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted intracellular proteins Show all		81 aa 8.2 kDa	No	0
CDIP1-015 ENSP00000467058 ENST00000566234	K7ENR4 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	Predicted intracellular proteins Show all		29 aa 2.9 kDa	No	0
CDIP1-017 ENSP00000466186 ENST00000589890	K7ELR4 [Direct mapping] Cell death-inducing p53-target protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		152 aa 15.6 kDa	No	0

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The Human Protein Atlas

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