Cell atlas - CMTM1 - The Human Protein Atlas

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CMTM1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	CMTM1
Gene description	CKLF-like MARVEL transmembrane domain containing 1
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA013801
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA013801	A-431	Nucleoplasm
	HPA013801	U-2 OS	Nucleoplasm
	HPA013801	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	CMTM1 (HGNC Symbol)
Synonyms	CKLFH, CKLFH1a, CKLFSF1
Description	CKLF-like MARVEL transmembrane domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011]
Chromosome	16
Cytoband	q21
Chromosome location (bp)	66566393 - 66579137
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000089505 (version 83.38)
Entrez gene	113540
UniProt	Q8IZ96 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IZ96
Antibodypedia	CMTM1 antibodies

PROTEIN BROWSER

CMTM1-001	CMTM1-002	CMTM1-005	CMTM1-006	CMTM1-007	CMTM1-013	CMTM1-015	CMTM1-017	CMTM1-019	CMTM1-026

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CMTM1-001 ENSP00000368814 ENST00000379500	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	286 aa 31.1 kDa	No	4
CMTM1-002 ENSP00000331428 ENST00000332695	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016021 [integral component of membrane] Show all	122 aa 13 kDa	No	2
CMTM1-005 ENSP00000337119 ENST00000336328	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016021 [integral component of membrane] Show all	116 aa 12.5 kDa	No	2
CMTM1-006 ENSP00000435786 ENST00000533953	E9PIL3 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	238 aa 25.5 kDa	No	2
CMTM1-007 ENSP00000432398 ENST00000528324	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016021 [integral component of membrane] Show all	114 aa 12.6 kDa	No	4
CMTM1-013 ENSP00000432687 ENST00000531885	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016021 [integral component of membrane] Show all	61 aa 6.6 kDa	No	1
CMTM1-015 ENSP00000405729 ENST00000457188	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	169 aa 18.6 kDa	No	5
CMTM1-017 ENSP00000434434 ENST00000529506	A0A0A0MTE4 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	70 aa 7.8 kDa	No	1
CMTM1-019 ENSP00000435020 ENST00000533666	Q8IZ96 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Transporters Transporter channels and pores Predicted intracellular proteins Show all	GO:0005125 [cytokine activity] GO:0005615 [extracellular space] GO:0006935 [chemotaxis] GO:0016021 [integral component of membrane] Show all	28 aa 3 kDa	No	0
CMTM1-026 ENSP00000330061 ENST00000328020	E9PAX0 [Direct mapping] CKLF-like MARVEL transmembrane domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	231 aa 25.1 kDa	No	3

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.