Expression of RBM41 in cancer - Summary - The Human Protein Atlas

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RBM41

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RBM41
Gene description	RNA binding motif protein 41
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membranous expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA042881
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042881

GENE INFORMATION
Gene name	RBM41 (HGNC Symbol)
Synonyms	FLJ11016
Description	RNA binding motif protein 41 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	q22.3
Chromosome location (bp)	107064420 - 107118823
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000089682 (version 83.38)
Entrez gene	55285
UniProt	Q96IZ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q96IZ5
Antibodypedia	RBM41 antibodies

PROTEIN BROWSER

RBM41-001	RBM41-002	RBM41-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM41-001 ENSP00000361565 ENST00000372487	Q96IZ5 [Direct mapping] RNA-binding protein 41 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000398 [mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005689 [U12-type spliceosomal complex] GO:0030626 [U12 snRNA binding] GO:0032502 [developmental process] GO:0097157 [pre-mRNA intronic binding] Show all	405 aa 46.3 kDa	No	0
RBM41-002 ENSP00000361557 ENST00000372479	Q96IZ5 [Direct mapping] RNA-binding protein 41 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000398 [mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0005689 [U12-type spliceosomal complex] GO:0030626 [U12 snRNA binding] GO:0032502 [developmental process] GO:0097157 [pre-mRNA intronic binding] Show all	413 aa 47.1 kDa	No	0
RBM41-008 ENSP00000405522 ENST00000434854	H0Y6F9 [Direct mapping] RNA-binding protein 41 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		203 aa 23.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.