Expression of ANKRD24 in cancer - Summary - The Human Protein Atlas

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ANKRD24

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANKRD24
Gene description	Ankyrin repeat domain 24
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (Karpas-707, U-266/70)
HPA (normal tissue):	Tissue enhanced (cerebral cortex, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA041534 , HPA048498
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (favourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041534	HPA048498

GENE INFORMATION
Gene name	ANKRD24 (HGNC Symbol)
Synonyms	KIAA1981
Description	Ankyrin repeat domain 24 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	4183354 - 4224814
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000089847 (version 83.38)
Entrez gene	170961
UniProt	Q8TF21 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TF21
Antibodypedia	ANKRD24 antibodies

PROTEIN BROWSER

ANKRD24-001	ANKRD24-002	ANKRD24-003	ANKRD24-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD24-001 ENSP00000470227 ENST00000597689	M0QZ18 [Direct mapping] Ankyrin repeat domain-containing protein 24 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	840 aa 90.2 kDa	No	0
ANKRD24-002 ENSP00000262970 ENST00000262970	Q8TF21 [Direct mapping] Ankyrin repeat domain-containing protein 24 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	1236 aa 132.4 kDa	No	0
ANKRD24-003 ENSP00000471252 ENST00000600132	Q8TF21 [Direct mapping] Ankyrin repeat domain-containing protein 24 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	1146 aa 124.2 kDa	No	0
ANKRD24-201 ENSP00000321731 ENST00000318934	Q8TF21 [Direct mapping] Ankyrin repeat domain-containing protein 24 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	1146 aa 124.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.