Expression of YPEL3 in cancer - Summary - The Human Protein Atlas

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YPEL3

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	YPEL3
Gene description	Yippee-like 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 2 antibodies. HPA030501 , HPA045621
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable).
Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA030501	HPA045621

GENE INFORMATION
Gene name	YPEL3 (HGNC Symbol)
Synonyms	MGC10500
Description	Yippee-like 3 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p11.2
Chromosome location (bp)	30092314 - 30096915
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000090238 (version 83.38)
Entrez gene	83719
UniProt	P61236 (UniProt - Evidence at transcript level)
neXtProt	NX_P61236
Antibodypedia	YPEL3 antibodies

PROTEIN BROWSER

YPEL3-001	YPEL3-002	YPEL3-003	YPEL3-007	YPEL3-008	YPEL3-009	YPEL3-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YPEL3-001 ENSP00000381821 ENST00000398841	P61236 [Direct mapping] Protein yippee-like 3 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0005730 [nucleolus] GO:2000774 [positive regulation of cellular senescence] Show all	157 aa 17.5 kDa	No	0
YPEL3-002 ENSP00000381818 ENST00000398838	P61236 [Direct mapping] Protein yippee-like 3 A0A024R624 [Target identity:100%; Query identity:100%] Protein yippee-like Show all	Predicted intracellular proteins Show all	GO:0005730 [nucleolus] GO:2000774 [positive regulation of cellular senescence] Show all	119 aa 13.6 kDa	No	0
YPEL3-003 ENSP00000456825 ENST00000562641	A0A0B4J290 [Direct mapping] Protein yippee-like Show all	Phobius predicted secreted proteins Predicted intracellular proteins Show all		137 aa 14.9 kDa	No	0
YPEL3-007 ENSP00000456427 ENST00000566595	P61236 [Direct mapping] Protein yippee-like 3 A0A024R624 [Target identity:100%; Query identity:100%] Protein yippee-like Show all	Predicted intracellular proteins Show all	GO:0005730 [nucleolus] GO:2000774 [positive regulation of cellular senescence] Show all	119 aa 13.6 kDa	No	0
YPEL3-008 ENSP00000457976 ENST00000563788	P61236 [Direct mapping] Protein yippee-like 3 A0A024R624 [Target identity:100%; Query identity:100%] Protein yippee-like Show all	Predicted intracellular proteins Show all	GO:0005730 [nucleolus] GO:2000774 [positive regulation of cellular senescence] Show all	119 aa 13.6 kDa	No	0
YPEL3-009 ENSP00000454350 ENST00000565110	H3BME7 [Direct mapping] Protein yippee-like Show all	Predicted intracellular proteins Show all		103 aa 11.6 kDa	No	0
YPEL3-010 ENSP00000457598 ENST00000566134	H3BUE2 [Direct mapping] Protein yippee-like 3 Show all	Predicted intracellular proteins Show all		75 aa 8.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.