Expression of RBM27 in cancer - Summary - The Human Protein Atlas

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RBM27

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RBM27
Gene description	RNA binding motif protein 27
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Mainly nucelar expression in most tissues, cytoplasmic expression was also observed.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA035944 , HPA036422
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA035944	HPA036422

GENE INFORMATION
Gene name	RBM27 (HGNC Symbol)
Synonyms	ARRS1, KIAA1311, Psc1, ZC3H20
Description	RNA binding motif protein 27 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q32
Chromosome location (bp)	146203600 - 146289132
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000091009 (version 83.38)
Entrez gene	54439
UniProt	Q9P2N5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P2N5
Antibodypedia	RBM27 antibodies

PROTEIN BROWSER

RBM27-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM27-001 ENSP00000265271 ENST00000265271	Q9P2N5 [Direct mapping] RNA-binding protein 27 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006397 [mRNA processing] GO:0016607 [nuclear speck] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	1060 aa 118.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.