Expression of GPATCH2 in cancer - Summary - The Human Protein Atlas

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GPATCH2

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GPATCH2
Gene description	G patch domain containing 2
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nuclear and cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA027181 , HPA027322
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027181	HPA027322

GENE INFORMATION
Gene name	GPATCH2 (HGNC Symbol)
Synonyms	CT110, FLJ10252, GPATC2, PPP1R30
Description	G patch domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q41
Chromosome location (bp)	217426992 - 217631082
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000092978 (version 83.38)
Entrez gene	55105
UniProt	Q9NW75 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NW75
Antibodypedia	GPATCH2 antibodies

PROTEIN BROWSER

GPATCH2-001	GPATCH2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPATCH2-001 ENSP00000355902 ENST00000366935	Q9NW75 [Direct mapping] G patch domain-containing protein 2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005730 [nucleolus] GO:0010923 [negative regulation of phosphatase activity] GO:0016607 [nuclear speck] Show all	528 aa 58.9 kDa	No	0
GPATCH2-002 ENSP00000355901 ENST00000366934	Q9NW75 [Direct mapping] G patch domain-containing protein 2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005730 [nucleolus] GO:0010923 [negative regulation of phosphatase activity] GO:0016607 [nuclear speck] Show all	376 aa 42.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.