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XYLB

GENERAL INFORMATION

Gene name

 XYLB

Gene description

 Xylulokinase homolog (H. influenzae)

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Tissue enhanced (liver)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA037863
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA037863

GENE INFORMATION

Gene name

 XYLB (HGNC Symbol)

Synonyms

 FLJ10343, FLJ12539

Description

 Xylulokinase homolog (H. influenzae) (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism. [provided by RefSeq, Aug 2009]

Chromosome

 3

Cytoband

 p22.2

Chromosome location (bp)

 38346760 - 38421348

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000093217 (version 83.38)

Entrez gene

 9942

UniProt

 O75191 (UniProt - Evidence at protein level)

neXtProt

 NX_O75191

Antibodypedia

 XYLB antibodies

PROTEIN BROWSER
XYLB-001
XYLB-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
XYLB-001
ENSP00000207870
ENST00000207870
O75191 [Direct mapping]
Xylulose kinase
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Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0004856 [xylulokinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0005997 [xylulose metabolic process]
GO:0005998 [xylulose catabolic process]
GO:0006091 [generation of precursor metabolites and energy]
GO:0016773 [phosphotransferase activity, alcohol group as acceptor]
GO:0019640 [glucuronate catabolic process to xylulose 5-phosphate]
GO:0042732 [D-xylose metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046835 [carbohydrate phosphorylation]
GO:0070062 [extracellular exosome]
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 536 aa
58.4 kDa 		No 0
XYLB-003
ENSP00000412282
ENST00000427323
C9J0N9 [Direct mapping]
Xylulose kinase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005737 [cytoplasm]
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 66 aa
7.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.