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ARCN1

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GENERAL INFORMATION

Gene name

 ARCN1

Gene description

 Archain 1

Protein class

 Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the Golgi apparatus & vesicles.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Golgi apparatus (validated), Vesicles (validated)

Mouse

 Localized to the Vesicles in mouse cells.

DATA RELIABILITY

Reliability score

 Validated based on 2 antibodies.
HPA037573 , HPA044874
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ASSAYS
RNA expression
Human cells
Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the Golgi apparatus & vesicles.

Main location

 Golgi apparatus (validated), Vesicles (validated)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA037573 A-431 Golgi apparatus
Vesicles
Cytosol
HPA037573 U-2 OS Golgi apparatus
Vesicles
HPA037573 U-251 MG Golgi apparatus
Vesicles
Cytosol
HPA044874 U-2 OS Vesicles
HPA044874 U-251 MG Vesicles

MOUSE CELLS

Main location

 Vesicles

Mouse gene

 ENSMUSG00000032096 (version 83)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location
HPA044874 NIH 3T3 Vesicles

GENE INFORMATION

Gene name

 ARCN1 (HGNC Symbol)

Synonyms

 COPD

Description

 Archain 1 (HGNC Symbol)

Entrez gene summary

 This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q23.3

Chromosome location (bp)

 118572390 - 118603033

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000095139 (version 83.38)

Entrez gene

 372

UniProt

 P48444 (UniProt - Evidence at protein level)

neXtProt

 NX_P48444

Antibodypedia

 ARCN1 antibodies

PROTEIN BROWSER
ARCN1-001
ARCN1-002
ARCN1-003
ARCN1-004
ARCN1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARCN1-001
ENSP00000264028
ENST00000264028
P48444 [Direct mapping]
Coatomer subunit delta
B0YIW5 [Target identity:100%; Query identity:100%]
Archain 1, isoform CRA_b; Coatomer subunit delta variant 1; cDNA, FLJ92603, Homo sapiens archain 1 (ARCN1), mRNA
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   Phobius predicted secreted proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0006810 [transport]
GO:0006886 [intracellular protein transport]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0008344 [adult locomotory behavior]
GO:0016020 [membrane]
GO:0021691 [cerebellar Purkinje cell layer maturation]
GO:0030126 [COPI vesicle coat]
GO:0030137 [COPI-coated vesicle]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043473 [pigmentation]
GO:0044822 [poly(A) RNA binding]
GO:0048193 [Golgi vesicle transport]
GO:0048205 [COPI coating of Golgi vesicle]
GO:0061024 [membrane organization]
Show all
 511 aa
57.2 kDa 		No 0
ARCN1-002
ENSP00000431676
ENST00000534182
E9PK34 [Direct mapping]
Coatomer subunit delta
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006810 [transport]
Show all
 83 aa
9.1 kDa 		Yes 0
ARCN1-003
ENSP00000352385
ENST00000359415
B0YIW6 [Direct mapping]
Archain 1, isoform CRA_a; Coatomer subunit delta; Coatomer subunit delta variant 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0006810 [transport]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 552 aa
61.6 kDa 		No 0
ARCN1-004
ENSP00000376599
ENST00000392859
P48444 [Direct mapping]
Coatomer subunit delta
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0006810 [transport]
GO:0006886 [intracellular protein transport]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0016020 [membrane]
GO:0030126 [COPI vesicle coat]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0044822 [poly(A) RNA binding]
GO:0048205 [COPI coating of Golgi vesicle]
GO:0061024 [membrane organization]
Show all
 423 aa
47.2 kDa 		No 0
ARCN1-201
ENSP00000482114
ENST00000614498
Q6P1Q5 [Direct mapping]
ARCN1 protein; Coatomer subunit delta
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006810 [transport]
GO:0015031 [protein transport]
Show all
 189 aa
21.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.