Expression of TDRD1 in cancer - Summary - The Human Protein Atlas

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TDRD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TDRD1
Gene description	Tudor domain containing 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (prostate cancer)
HPA (cell line):	Cell line enhanced (MCF7, RH-30, SK-BR-3, U-266/84)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results.
Reliability score	Uncertain based on 2 antibodies. HPA037729 , HPA037730
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037729	HPA037730

GENE INFORMATION
Gene name	TDRD1 (HGNC Symbol)
Synonyms	CT41.1
Description	Tudor domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q25.3
Chromosome location (bp)	114179270 - 114232304
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000095627 (version 83.38)
Entrez gene	56165
UniProt	Q9BXT4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXT4
Antibodypedia	TDRD1 antibodies

PROTEIN BROWSER

TDRD1-001	TDRD1-002	TDRD1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TDRD1-001 ENSP00000358286 ENST00000369280	H9KV62 [Direct mapping] Tudor domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0046872 [metal ion binding] Show all	1104 aa 123.8 kDa	No	0
TDRD1-002 ENSP00000358288 ENST00000369282	H9KV63 [Direct mapping] Tudor domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0046872 [metal ion binding] Show all	1113 aa 124.7 kDa	No	0
TDRD1-201 ENSP00000251864 ENST00000251864	Q9BXT4 [Direct mapping] Tudor domain-containing protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0007275 [multicellular organismal development] GO:0007281 [germ cell development] GO:0007283 [spermatogenesis] GO:0010467 [gene expression] GO:0030529 [ribonucleoprotein complex] GO:0031047 [gene silencing by RNA] GO:0033391 [chromatoid body] GO:0034587 [piRNA metabolic process] GO:0043046 [DNA methylation involved in gamete generation] GO:0043186 [P granule] GO:0046872 [metal ion binding] GO:0051321 [meiotic cell cycle] GO:0071546 [pi-body] Show all	1189 aa 132.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.