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Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

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Score

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NRP1
  • TISSUE

  • CELL

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

NRP1

Gene description

Neuropilin 1

Protein class

Cancer-related genes
CD markers
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

14
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous granular cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 2 antibodies.
HPA030278 , CAB004511
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

NRP1 (HGNC Symbol)

Synonyms

CD304, NRP, VEGF165R

Description

Neuropilin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

10

Cytoband

p11.22

Chromosome location (bp)

33177492 - 33336262

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099250 (version 83.38)

Entrez gene

8829

UniProt

O14786 (UniProt - Evidence at protein level)

neXtProt

NX_O14786

Antibodypedia

NRP1 antibodies

PROTEIN BROWSER

«
NRP1-001
NRP1-002
NRP1-003
NRP1-004
NRP1-005
NRP1-006
NRP1-007
NRP1-008
NRP1-009
NRP1-010
NRP1-011
NRP1-201
NRP1-202
NRP1-203
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NRP1-001
ENSP00000265371
ENST00000265371
O14786 [Direct mapping]
Neuropilin-1
Show all
CD markers
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0001569 [patterning of blood vessels]
GO:0001764 [neuron migration]
GO:0001938 [positive regulation of endothelial cell proliferation]
GO:0002040 [sprouting angiogenesis]
GO:0002042 [cell migration involved in sprouting angiogenesis]
GO:0002116 [semaphorin receptor complex]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005829 [cytosol]
GO:0005883 [neurofilament]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0007267 [cell-cell signaling]
GO:0007411 [axon guidance]
GO:0007413 [axonal fasciculation]
GO:0007507 [heart development]
GO:0008045 [motor neuron axon guidance]
GO:0008201 [heparin binding]
GO:0009611 [response to wounding]
GO:0009887 [organ morphogenesis]
GO:0009986 [cell surface]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0014911 [positive regulation of smooth muscle cell migration]
GO:0015026 [coreceptor activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016358 [dendrite development]
GO:0016477 [cell migration]
GO:0017154 [semaphorin receptor activity]
GO:0019838 [growth factor binding]
GO:0019955 [cytokine binding]
GO:0021612 [facial nerve structural organization]
GO:0021636 [trigeminal nerve morphogenesis]
GO:0021637 [trigeminal nerve structural organization]
GO:0021649 [vestibulocochlear nerve structural organization]
GO:0021675 [nerve development]
GO:0021785 [branchiomotor neuron axon guidance]
GO:0021828 [gonadotrophin-releasing hormone neuronal migration to the hypothalamus]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030517 [negative regulation of axon extension]
GO:0031290 [retinal ganglion cell axon guidance]
GO:0031410 [cytoplasmic vesicle]
GO:0035729 [cellular response to hepatocyte growth factor stimulus]
GO:0035767 [endothelial cell chemotaxis]
GO:0035924 [cellular response to vascular endothelial growth factor stimulus]
GO:0036486 [ventral trunk neural crest cell migration]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0038085 [vascular endothelial growth factor binding]
GO:0038190 [VEGF-activated neuropilin signaling pathway]
GO:0043025 [neuronal cell body]
GO:0043049 [otic placode formation]
GO:0043235 [receptor complex]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0046872 [metal ion binding]
GO:0048008 [platelet-derived growth factor receptor signaling pathway]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048012 [hepatocyte growth factor receptor signaling pathway]
GO:0048485 [sympathetic nervous system development]
GO:0048666 [neuron development]
GO:0048841 [regulation of axon extension involved in axon guidance]
GO:0048842 [positive regulation of axon extension involved in axon guidance]
GO:0048843 [negative regulation of axon extension involved in axon guidance]
GO:0048844 [artery morphogenesis]
GO:0048846 [axon extension involved in axon guidance]
GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation]
GO:0050918 [positive chemotaxis]
GO:0060301 [positive regulation of cytokine activity]
GO:0060385 [axonogenesis involved in innervation]
GO:0060627 [regulation of vesicle-mediated transport]
GO:0060666 [dichotomous subdivision of terminal units involved in salivary gland branching]
GO:0060978 [angiogenesis involved in coronary vascular morphogenesis]
GO:0060982 [coronary artery morphogenesis]
GO:0061299 [retina vasculature morphogenesis in camera-type eye]
GO:0061441 [renal artery morphogenesis]
GO:0061549 [sympathetic ganglion development]
GO:0061551 [trigeminal ganglion development]
GO:0061552 [ganglion morphogenesis]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0071526 [semaphorin-plexin signaling pathway]
GO:0071679 [commissural neuron axon guidance]
GO:0090259 [regulation of retinal ganglion cell axon guidance]
GO:0097102 [endothelial tip cell fate specification]
GO:0097374 [sensory neuron axon guidance]
GO:0097443 [sorting endosome]
GO:0097490 [sympathetic neuron projection extension]
GO:0097491 [sympathetic neuron projection guidance]
GO:1901166 [neural crest cell migration involved in autonomic nervous system development]
GO:1901998 [toxin transport]
GO:1902285 [semaphorin-plexin signaling pathway involved in neuron projection guidance]
GO:1902287 [semaphorin-plexin signaling pathway involved in axon guidance]
GO:1902336 [positive regulation of retinal ganglion cell axon guidance]
GO:1902378 [VEGF-activated neuropilin signaling pathway involved in axon guidance]
GO:1902946 [protein localization to early endosome]
GO:1903375 [facioacoustic ganglion development]
GO:2001237 [negative regulation of extrinsic apoptotic signaling pathway]
Show all
923 aa
103.1 kDa
Yes 1
NRP1-002
ENSP00000364009
ENST00000374875
Q5JWQ6 [Direct mapping]
Neuropilin-1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0007411 [axon guidance]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0017154 [semaphorin receptor activity]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0046872 [metal ion binding]
GO:0071526 [semaphorin-plexin signaling pathway]
Show all
735 aa
82 kDa
No 1
NRP1-003
ENSP00000363955
ENST00000374822
O14786 [Direct mapping]
Neuropilin-1
Show all
CD markers
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0001569 [patterning of blood vessels]
GO:0001764 [neuron migration]
GO:0001938 [positive regulation of endothelial cell proliferation]
GO:0002040 [sprouting angiogenesis]
GO:0002042 [cell migration involved in sprouting angiogenesis]
GO:0002116 [semaphorin receptor complex]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0007267 [cell-cell signaling]
GO:0007411 [axon guidance]
GO:0008201 [heparin binding]
GO:0009887 [organ morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0014911 [positive regulation of smooth muscle cell migration]
GO:0015026 [coreceptor activity]
GO:0016021 [integral component of membrane]
GO:0017154 [semaphorin receptor activity]
GO:0019838 [growth factor binding]
GO:0019955 [cytokine binding]
GO:0021675 [nerve development]
GO:0030424 [axon]
GO:0031290 [retinal ganglion cell axon guidance]
GO:0031410 [cytoplasmic vesicle]
GO:0035729 [cellular response to hepatocyte growth factor stimulus]
GO:0035767 [endothelial cell chemotaxis]
GO:0035924 [cellular response to vascular endothelial growth factor stimulus]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0038085 [vascular endothelial growth factor binding]
GO:0038190 [VEGF-activated neuropilin signaling pathway]
GO:0043235 [receptor complex]
GO:0046872 [metal ion binding]
GO:0048008 [platelet-derived growth factor receptor signaling pathway]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048012 [hepatocyte growth factor receptor signaling pathway]
GO:0048842 [positive regulation of axon extension involved in axon guidance]
GO:0048844 [artery morphogenesis]
GO:0048846 [axon extension involved in axon guidance]
GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation]
GO:0050918 [positive chemotaxis]
GO:0060301 [positive regulation of cytokine activity]
GO:0060385 [axonogenesis involved in innervation]
GO:0060627 [regulation of vesicle-mediated transport]
GO:0060978 [angiogenesis involved in coronary vascular morphogenesis]
GO:0061299 [retina vasculature morphogenesis in camera-type eye]
GO:0061549 [sympathetic ganglion development]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0071526 [semaphorin-plexin signaling pathway]
GO:0071679 [commissural neuron axon guidance]
GO:0090259 [regulation of retinal ganglion cell axon guidance]
GO:0097102 [endothelial tip cell fate specification]
GO:0097443 [sorting endosome]
GO:0097490 [sympathetic neuron projection extension]
GO:0097491 [sympathetic neuron projection guidance]
GO:1901166 [neural crest cell migration involved in autonomic nervous system development]
GO:1902285 [semaphorin-plexin signaling pathway involved in neuron projection guidance]
GO:1902336 [positive regulation of retinal ganglion cell axon guidance]
GO:1902946 [protein localization to early endosome]
Show all
644 aa
71.9 kDa
Yes 0
NRP1-004
ENSP00000363954
ENST00000374821
O14786 [Direct mapping]
Neuropilin-1
Show all
CD markers
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0001569 [patterning of blood vessels]
GO:0001764 [neuron migration]
GO:0001938 [positive regulation of endothelial cell proliferation]
GO:0002040 [sprouting angiogenesis]
GO:0002042 [cell migration involved in sprouting angiogenesis]
GO:0002116 [semaphorin receptor complex]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0007267 [cell-cell signaling]
GO:0007411 [axon guidance]
GO:0008201 [heparin binding]
GO:0009887 [organ morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0014911 [positive regulation of smooth muscle cell migration]
GO:0015026 [coreceptor activity]
GO:0016021 [integral component of membrane]
GO:0017154 [semaphorin receptor activity]
GO:0019838 [growth factor binding]
GO:0019955 [cytokine binding]
GO:0021675 [nerve development]
GO:0030424 [axon]
GO:0031290 [retinal ganglion cell axon guidance]
GO:0031410 [cytoplasmic vesicle]
GO:0035729 [cellular response to hepatocyte growth factor stimulus]
GO:0035767 [endothelial cell chemotaxis]
GO:0035924 [cellular response to vascular endothelial growth factor stimulus]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0038085 [vascular endothelial growth factor binding]
GO:0038190 [VEGF-activated neuropilin signaling pathway]
GO:0043235 [receptor complex]
GO:0046872 [metal ion binding]
GO:0048008 [platelet-derived growth factor receptor signaling pathway]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048012 [hepatocyte growth factor receptor signaling pathway]
GO:0048842 [positive regulation of axon extension involved in axon guidance]
GO:0048844 [artery morphogenesis]
GO:0048846 [axon extension involved in axon guidance]
GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation]
GO:0050918 [positive chemotaxis]
GO:0060301 [positive regulation of cytokine activity]
GO:0060385 [axonogenesis involved in innervation]
GO:0060627 [regulation of vesicle-mediated transport]
GO:0060978 [angiogenesis involved in coronary vascular morphogenesis]
GO:0061299 [retina vasculature morphogenesis in camera-type eye]
GO:0061549 [sympathetic ganglion development]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0071526 [semaphorin-plexin signaling pathway]
GO:0071679 [commissural neuron axon guidance]
GO:0090259 [regulation of retinal ganglion cell axon guidance]
GO:0097102 [endothelial tip cell fate specification]
GO:0097443 [sorting endosome]
GO:0097490 [sympathetic neuron projection extension]
GO:0097491 [sympathetic neuron projection guidance]
GO:1901166 [neural crest cell migration involved in autonomic nervous system development]
GO:1902285 [semaphorin-plexin signaling pathway involved in neuron projection guidance]
GO:1902336 [positive regulation of retinal ganglion cell axon guidance]
GO:1902946 [protein localization to early endosome]
Show all
609 aa
68.4 kDa
Yes 0
NRP1-005
ENSP00000363956
ENST00000374823
Q5T7F0 [Direct mapping]
Neuropilin-1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0007411 [axon guidance]
GO:0017154 [semaphorin receptor activity]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0046872 [metal ion binding]
GO:0071526 [semaphorin-plexin signaling pathway]
Show all
704 aa
79 kDa
Yes 0
NRP1-006
ENSP00000408911
ENST00000432372
Q5JWQ4 [Direct mapping]
Neuropilin-1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
597 aa
67.3 kDa
Yes 0
NRP1-007
ENSP00000393071
ENST00000431894
H0Y4N6 [Direct mapping]
Neuropilin-1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
100 aa
10.6 kDa
No 0
NRP1-008
ENSP00000416147
ENST00000418675
H0Y7Z2 [Direct mapping]
Neuropilin-1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
77 aa
7.9 kDa
No 0
NRP1-009
ENSP00000390447
ENST00000413802
Q5JWQ2 [Direct mapping]
Neuropilin-1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
105 aa
11.4 kDa
No 1
NRP1-010
ENSP00000476896
ENST00000466932
V9GYL7 [Direct mapping]
Neuropilin-1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
60 aa
6.9 kDa
No 0
NRP1-011
ENSP00000390567
ENST00000455749
H0Y4A0 [Direct mapping]
Neuropilin-1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
170 aa
19 kDa
No 0
NRP1-201
ENSP00000363949
ENST00000374816
E7EX60 [Direct mapping]
Neuropilin-1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0007411 [axon guidance]
GO:0017154 [semaphorin receptor activity]
GO:0038084 [vascular endothelial growth factor signaling pathway]
Show all
641 aa
72.1 kDa
Yes 0
NRP1-202
ENSP00000364001
ENST00000374867
O14786 [Direct mapping]
Neuropilin-1
Show all
CD markers
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0001569 [patterning of blood vessels]
GO:0001764 [neuron migration]
GO:0001938 [positive regulation of endothelial cell proliferation]
GO:0002040 [sprouting angiogenesis]
GO:0002042 [cell migration involved in sprouting angiogenesis]
GO:0002116 [semaphorin receptor complex]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005769 [early endosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0007267 [cell-cell signaling]
GO:0007411 [axon guidance]
GO:0008201 [heparin binding]
GO:0009887 [organ morphogenesis]
GO:0010595 [positive regulation of endothelial cell migration]
GO:0014911 [positive regulation of smooth muscle cell migration]
GO:0015026 [coreceptor activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0017154 [semaphorin receptor activity]
GO:0019838 [growth factor binding]
GO:0019955 [cytokine binding]
GO:0021675 [nerve development]
GO:0030424 [axon]
GO:0031290 [retinal ganglion cell axon guidance]
GO:0031410 [cytoplasmic vesicle]
GO:0035729 [cellular response to hepatocyte growth factor stimulus]
GO:0035767 [endothelial cell chemotaxis]
GO:0035924 [cellular response to vascular endothelial growth factor stimulus]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0038085 [vascular endothelial growth factor binding]
GO:0038190 [VEGF-activated neuropilin signaling pathway]
GO:0043235 [receptor complex]
GO:0046872 [metal ion binding]
GO:0048008 [platelet-derived growth factor receptor signaling pathway]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048012 [hepatocyte growth factor receptor signaling pathway]
GO:0048842 [positive regulation of axon extension involved in axon guidance]
GO:0048844 [artery morphogenesis]
GO:0048846 [axon extension involved in axon guidance]
GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation]
GO:0050918 [positive chemotaxis]
GO:0060301 [positive regulation of cytokine activity]
GO:0060385 [axonogenesis involved in innervation]
GO:0060627 [regulation of vesicle-mediated transport]
GO:0060978 [angiogenesis involved in coronary vascular morphogenesis]
GO:0061299 [retina vasculature morphogenesis in camera-type eye]
GO:0061549 [sympathetic ganglion development]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0071526 [semaphorin-plexin signaling pathway]
GO:0071679 [commissural neuron axon guidance]
GO:0090259 [regulation of retinal ganglion cell axon guidance]
GO:0097102 [endothelial tip cell fate specification]
GO:0097443 [sorting endosome]
GO:0097490 [sympathetic neuron projection extension]
GO:0097491 [sympathetic neuron projection guidance]
GO:1901166 [neural crest cell migration involved in autonomic nervous system development]
GO:1902285 [semaphorin-plexin signaling pathway involved in neuron projection guidance]
GO:1902336 [positive regulation of retinal ganglion cell axon guidance]
GO:1902946 [protein localization to early endosome]
Show all
923 aa
103.1 kDa
Yes 1
NRP1-203
ENSP00000379317
ENST00000395995
E9PEP6 [Direct mapping]
Neuropilin-1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
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GO:0001525 [angiogenesis]
GO:0005021 [vascular endothelial growth factor-activated receptor activity]
GO:0007411 [axon guidance]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0017154 [semaphorin receptor activity]
GO:0038084 [vascular endothelial growth factor signaling pathway]
GO:0046872 [metal ion binding]
GO:0071526 [semaphorin-plexin signaling pathway]
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906 aa
101.3 kDa
Yes 1

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