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MAST3

GENERAL INFORMATION

Gene name

 MAST3

Gene description

 Microtubule associated serine/threonine kinase 3

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA035061 , HPA035062
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable) and pancreatic cancer (favourable).
Head and neck cancer p<0.001
Pancreatic cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA035061
HPA035062

GENE INFORMATION

Gene name

 MAST3 (HGNC Symbol)

Synonyms

 KIAA0561

Description

 Microtubule associated serine/threonine kinase 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 18097793 - 18151692

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000099308 (version 83.38)

Entrez gene

 23031

UniProt

 O60307 (UniProt - Evidence at protein level)

neXtProt

 NX_O60307

Antibodypedia

 MAST3 antibodies

PROTEIN BROWSER
MAST3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAST3-001
ENSP00000262811
ENST00000262811
O60307 [Direct mapping]
Microtubule-associated serine/threonine-protein kinase 3
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   AGC Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000287 [magnesium ion binding]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005622 [intracellular]
GO:0006468 [protein phosphorylation]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0035556 [intracellular signal transduction]
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 1309 aa
143.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.