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Group enriched (HL-60, K-562, Karpas-707, U-2 OS, U-266/70, U-266/84)
HPA (normal tissue):
Tissue enriched (testis)
Protein evidence
Evidence at protein level
ANTIBODY IHC RELIABILITY
Reliability score
Pending cancer tissue analysis.
PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all
RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (testis cancer)
PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY
GENE INFORMATION
Gene name
MAGEB2 (HGNC Symbol)
Synonyms
CT3.2, DAM6, MAGE-XP-2, MGC26438
Description
Melanoma antigen family B2 (HGNC Symbol)
Entrez gene summary
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
