Tissue expression of GTPBP1 - Summary - The Human Protein Atlas

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GTPBP1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GTPBP1
Gene description	GTP binding protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression, highly abundant in stromal cells.

DATA RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA003166
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	GTPBP1 (HGNC Symbol)
Synonyms	GP-1, HSPC018
Description	GTP binding protein 1 (HGNC Symbol)
Entrez gene summary	This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]
Chromosome	22
Cytoband	q13.1
Chromosome location (bp)	38705723 - 38738299
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100226 (version 83.38)
Entrez gene	9567
UniProt	O00178 (UniProt - Evidence at protein level)
neXtProt	NX_O00178
Antibodypedia	GTPBP1 antibodies

PROTEIN BROWSER

GTPBP1-001	GTPBP1-003	GTPBP1-005	GTPBP1-010	GTPBP1-011	GTPBP1-018

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GTPBP1-001 ENSP00000216044 ENST00000216044	O00178 [Direct mapping] GTP-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000177 [cytoplasmic exosome (RNase complex)] GO:0003743 [translation initiation factor activity] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006413 [translational initiation] GO:0006955 [immune response] GO:0007165 [signal transduction] GO:0016020 [membrane] GO:0044822 [poly(A) RNA binding] GO:0061014 [positive regulation of mRNA catabolic process] Show all	669 aa 72.5 kDa	No	0
GTPBP1-003 ENSP00000442881 ENST00000484657	F5H716 [Direct mapping] GTP-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		152 aa 16.6 kDa	No	0
GTPBP1-005 ENSP00000439505 ENST00000488787	F5H257 [Direct mapping] GTP-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 9.6 kDa	No	0
GTPBP1-010 ENSP00000388147 ENST00000458073	B0QY59 [Direct mapping] GTP-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		349 aa 37.9 kDa	No	0
GTPBP1-011 ENSP00000442628 ENST00000470836	F5H7C0 [Direct mapping] GTP-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		39 aa 4.3 kDa	No	0
GTPBP1-018 ENSP00000437430 ENST00000489527	H0YF75 [Direct mapping] GTP-binding protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		40 aa 4.3 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.