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Cancer tissues were in general weakly stained or negative. Cases of cholangiocarcinomas, testicular, urothelial and gastric cancers showed moderate cytoplasmic staining.
Cancer tissues were weakly stained or negative. Cases of urothelial and breast cancers were moderately stained.
GENE INFORMATION
Gene name
SYNGR1
Synonyms
Description
Synaptogyrin 1 (HGNC Symbol)
Entrez gene summary
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008]