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A few cases of colorectal and prostate cancers along with a rare case of glioma, melanoma, thyroid and liver cancer showed moderate cytoplasmic positivity. Remaining malignant tissues were weakly stained or negative.
This gene is a member of the patatin-like phospholipase family; its encoded protein has been shown to inhibit transacylation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]