Cell atlas - SAMM50 - The Human Protein Atlas

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SAMM50

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TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	SAMM50
Gene description	SAMM50 sorting and assembly machinery component
Protein class	Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (validated)

DATA RELIABILITY
Reliability score	Validated based on 1 antibody. HPA034537
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (validated)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA034537	A-431	Mitochondria
	HPA034537	U-2 OS	Mitochondria
	HPA034537	U-251 MG	Mitochondria

GENE INFORMATION
Gene name	SAMM50 (HGNC Symbol)
Synonyms	CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W
Description	SAMM50 sorting and assembly machinery component (HGNC Symbol)
Entrez gene summary	This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.[provided by RefSeq, Jun 2011]
Chromosome	22
Cytoband	q13.31
Chromosome location (bp)	43955421 - 44010531
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100347 (version 83.38)
Entrez gene	25813
UniProt	Q9Y512 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y512
Antibodypedia	SAMM50 antibodies

PROTEIN BROWSER

SAMM50-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SAMM50-001 ENSP00000345445 ENST00000350028	Q9Y512 [Direct mapping] Sorting and assembly machinery component 50 homolog Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001401 [mitochondrial sorting and assembly machinery complex] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005743 [mitochondrial inner membrane] GO:0006626 [protein targeting to mitochondrion] GO:0016021 [integral component of membrane] GO:0019867 [outer membrane] GO:0033108 [mitochondrial respiratory chain complex assembly] GO:0042407 [cristae formation] GO:0044267 [cellular protein metabolic process] GO:0045040 [protein import into mitochondrial outer membrane] GO:0070062 [extracellular exosome] Show all	469 aa 52 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.