Fields »
ABOUT
HELP
BLOG
IFT27

GENERAL INFORMATION

Gene name

 IFT27

Gene description

 Intraflagellar transport 27

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in a several tissues, mainly in CNS.

DATA RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA018418
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 IFT27 (HGNC Symbol)

Synonyms

 BBS19, RABL4, RAYL

Description

 Intraflagellar transport 27 (HGNC Symbol)

Entrez gene summary

 This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Chromosome

 22

Cytoband

 q12.3

Chromosome location (bp)

 36758202 - 36776256

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000100360 (version 83.38)

Entrez gene

 11020

UniProt

 Q9BW83 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BW83

Antibodypedia

 IFT27 antibodies

PROTEIN BROWSER
IFT27-001
IFT27-002
IFT27-003
IFT27-005
IFT27-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IFT27-001
ENSP00000343593
ENST00000340630
Q9BW83 [Direct mapping]
Intraflagellar transport protein 27 homolog
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005929 [cilium]
GO:0006886 [intracellular protein transport]
GO:0006996 [organelle organization]
GO:0007165 [signal transduction]
GO:0007224 [smoothened signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0030992 [intraciliary transport particle B]
GO:0031514 [motile cilium]
GO:0032482 [Rab protein signal transduction]
GO:0042073 [intraciliary transport]
GO:0072372 [primary cilium]
GO:0097542 [ciliary tip]
Show all
 185 aa
20.4 kDa 		No 0
IFT27-002
ENSP00000392016
ENST00000417951
F5GZ09 [Direct mapping]
Intraflagellar transport protein 27 homolog
Show all
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 183 aa
19.7 kDa 		No 0
IFT27-003
ENSP00000399606
ENST00000440696
B1AH56 [Direct mapping]
Intraflagellar transport protein 27 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007264 [small GTPase mediated signal transduction]
GO:0032482 [Rab protein signal transduction]
Show all
 51 aa
5.7 kDa 		No 0
IFT27-005
ENSP00000390016
ENST00000430701
B1AH58 [Direct mapping]
Intraflagellar transport protein 27 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007264 [small GTPase mediated signal transduction]
GO:0032482 [Rab protein signal transduction]
Show all
 116 aa
12.7 kDa 		No 0
IFT27-201
ENSP00000393541
ENST00000433985
Q9BW83 [Direct mapping]
Intraflagellar transport protein 27 homolog
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005813 [centrosome]
GO:0005929 [cilium]
GO:0006886 [intracellular protein transport]
GO:0006996 [organelle organization]
GO:0007165 [signal transduction]
GO:0007224 [smoothened signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0030992 [intraciliary transport particle B]
GO:0031514 [motile cilium]
GO:0032482 [Rab protein signal transduction]
GO:0042073 [intraciliary transport]
GO:0072372 [primary cilium]
GO:0097225 [sperm midpiece]
GO:0097228 [sperm principal piece]
GO:0097542 [ciliary tip]
Show all
 186 aa
20.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.