Expression of SAMD15 in cancer - Summary - The Human Protein Atlas

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SAMD15

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SAMD15
Gene description	Sterile alpha motif domain containing 15
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in most tissues, most abundant in testis and CNS.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. External characterization data supports antibody staining.
Reliability score	Approved based on 2 antibodies. HPA030673 , HPA030677
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Cervical cancer

STAINING SUMMARY

HPA030673	HPA030677

GENE INFORMATION
Gene name	SAMD15 (HGNC Symbol)
Synonyms	C14orf174, FAM15A, FLJ35963
Description	Sterile alpha motif domain containing 15 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	77376689 - 77391497
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100583 (version 83.38)
Entrez gene	161394
UniProt	Q9P1V8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9P1V8
Antibodypedia	SAMD15 antibodies

PROTEIN BROWSER

SAMD15-001	SAMD15-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SAMD15-001 ENSP00000216471 ENST00000216471	Q9P1V8 [Direct mapping] Sterile alpha motif domain-containing protein 15 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	674 aa 77.2 kDa	No	0
SAMD15-003 ENSP00000450941 ENST00000533095	G3V2Z3 [Direct mapping] Sterile alpha motif domain-containing protein 15 Show all	Predicted intracellular proteins Show all		88 aa 9.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.